黄芪提取物治疗运动相关腿筋损伤:MRI治疗分析

IF 2.5 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES
Ziyu Song
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引用次数: 0

摘要

目的探讨黄芪提取物(AME)促进急性运动相关腘绳肌修复的磁共振成像(MRI)可行性。材料与方法将60例急性腘绳肌损伤患者随机分为自然愈合组(NH组)、皮质类固醇治疗组(CC组)和AME注射治疗组(AME组),每组20例。MRI分析损伤的位置、程度和分级。评估各治疗组血清乳酸脱氢酶(LDH)、肌酸激酶(CK)、丙二醛(MDA)、超氧化物歧化酶(SOD)、峰值扭矩(PT)、最大重复功(MRW)、总功(TW)和平均功率(AP)水平。结果smri检查显示肌肉损伤47例(78.3%),主要表现为肌间积液;肌腱损伤13例(21.7%),表现为信号增强或完全断裂。治疗后,两组间比较,损伤等级分布差异有统计学意义(χ2 = 6.235, P = 0.044), AME组与NH组损伤等级改善差异有统计学意义(χ2 = 4.127, P < 0.05)。NH组、CC组和AME组的良好转归率分别为65.0%、80.0%和90.0%。与CC组比较,AME组血清LDH、CK、MDA水平降低,SOD水平升高,PT、MRW、TW、AP水平升高(P < 0.05)。mri评估证实,AME治疗显著加速了功能恢复,减少了肌肉损伤和氧化应激标志物,并比自然愈合和皮质类固醇注射更有效地提高了mri评估的损伤等级。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Astragalus membranaceus extract for sports-related hamstring injuries: A therapeutic analysis with MRI

Objective

The aim of this study was to investigate the feasibility of Astragalus membranaceus extract (AME) in promoting acute sports-related hamstring muscle repair using magnetic resonance imaging (MRI).

Materials and methods

Sixty patients with acute hamstring muscle injuries were randomly assigned to three groups: natural healing group (NH group), corticosteroid treatment group (CC group), and AME injection treatment group (AME group), with 20 patients in each group. MRI was employed to analyze the location, extent, and grading of injuries. The levels of serum lactate dehydrogenase (LDH), creatine kinase (CK), malondialdehyde (MDA), superoxide dismutase (SOD), peak torque (PT), maximum repetition work (MRW), total work (TW), and average power (AP) were assessed for each treatment group.

Results

MRI examination revealed muscle injuries in 47 cases (78.3 %), primarily manifested as intermuscular effusion, and tendon injuries in 13 cases (21.7 %), characterized by increased signal intensity or complete rupture. After treatment, overall intergroup comparison revealed a statistically significant difference in injury grade distribution (χ2 = 6.235, P = 0.044), a significant difference in injury grade improvement the AME group and the NH group (χ2 = 4.127, P < 0.05). The rates of favorable outcomes in the NH, CC, and AME groups were 65.0 %, 80.0 %, and 90.0 %, respectively. Compared with the CC group, the AME group exhibited reduced serum levels of LDH, CK, and MDA, increased SOD levels, and elevated PT, MRW, TW, and AP levels (P < 0.05).

Conclusion

MRI assessment confirmed that AME treatment significantly accelerated functional recovery, reduced markers of muscle damage and oxidative stress, and improved MRI-assessed injury grades more effectively than both natural healing and corticosteroid injections.
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来源期刊
自引率
5.90%
发文量
130
审稿时长
16 weeks
期刊介绍: Journal of Radiation Research and Applied Sciences provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and applications of nuclear, radiation and isotopes in biology, medicine, drugs, biochemistry, microbiology, agriculture, entomology, food technology, chemistry, physics, solid states, engineering, environmental and applied sciences.
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