加速与强化内镜治疗胰腺壁外坏死：一项随机对照试验（ACCELERATE）

IF 12 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Clinical Gastroenterology and Hepatology Pub Date : 2025-08-18 DOI:10.1016/j.cgh.2025.08.007

Olsen GA MD, Schmidt PN MD PhD, Hadi A MD, Prahm AP MD, Werge MP MD PhD, Roug S MD, Schefte DF MD, Lauritsen ML MD, Hansen EF MD PhD, Novovic S MD PhD, Karstensen JG MD PhD

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引用次数: 0

摘要

内镜下强化治疗超声引导引流和坏死切除术已成为治疗胰腺壁脱性坏死（WON）的金标准；然而，大WON患者的住院时间（LOS）仍然相当可观。我们假设加速治疗方案可以减少大WON患者的LOS和主要并发症。

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Accelerated vs Step-Up Endoscopic Treatment for Pancreatic Walled-Off Necrosis: A Randomized Controlled Trial (ACCELERATE)

Endoscopic step-up treatment with ultrasound-guided drainage and necrosectomy has become the gold standard treatment of pancreatic walled-off necrosis (WON); however, the length of stay (LOS) in hospital of patients with large WON remains substantial. We hypothesized that an accelerated treatment protocol could reduce LOS and major complications in patients with large WON.

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来源期刊

Clinical Gastroenterology and Hepatology 医学-胃肠肝病学

CiteScore

16.90

自引率

4.80%

发文量

903

审稿时长

22 days

期刊介绍： Clinical Gastroenterology and Hepatology (CGH) is dedicated to offering readers a comprehensive exploration of themes in clinical gastroenterology and hepatology. Encompassing diagnostic, endoscopic, interventional, and therapeutic advances, the journal covers areas such as cancer, inflammatory diseases, functional gastrointestinal disorders, nutrition, absorption, and secretion. As a peer-reviewed publication, CGH features original articles and scholarly reviews, ensuring immediate relevance to the practice of gastroenterology and hepatology. Beyond peer-reviewed content, the journal includes invited key reviews and articles on endoscopy/practice-based technology, health-care policy, and practice management. Multimedia elements, including images, video abstracts, and podcasts, enhance the reader's experience. CGH remains actively engaged with its audience through updates and commentary shared via platforms such as Facebook and Twitter.