用巴特沃斯滤波器预重建滤波对111in - pentreotide SPECT图像质量和定量精度的影响：一个幻影研究

IF 2.8 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiography Pub Date : 2025-08-25 DOI:10.1016/j.radi.2025.103121

D. Hasegawa , T. Iguchi , M. Nakashima , K. Yoshitomi , M. Miyai , K. Kojima , T. Asahara

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引用次数: 0

摘要

本研究评估了在生长抑素受体闪烁成像中采用重建前后平滑滤波器的SPECT图像的图像质量和定量准确性。方法利用充满111In溶液的NEMA IEC体模体，对空间分辨率、噪声对比比（CNR）和定量精度进行了评估。使用西门子Symbia T16 SPECT/CT系统获得SPECT图像。定量精度是指从图像中准确估计出幻体中111In的放射性浓度的能力。SPECT重建采用三种方法：重建后高斯滤波（post-G）、重建前高斯滤波（pre-G）和重建前巴特沃斯滤波（pre-B）。为了验证每种滤波方法，将巴特沃斯滤波器的截止频率和高斯滤波器的半最大值全宽度（FWHM）分别更改为8种不同的设置。结果g后、g前和b前的fwhm分别为21.2、19.8和18.0 mm。37-mm球的cnr分别为47.2、63.8和69.5。在0.40 cycles/cm时，前b的误差率为12.0%，而在7.2 mm FWHM时，后g和前g的误差率分别为20.2%和22.0%。Pre-B在分辨率、CNR和定量精度方面优于其他方法。结论对于111in - pentreotide SPECT图像，在重建前对投影图像进行巴特沃斯滤波重建，在图像质量和定量精度上优于高斯滤波重建。该方法可以很容易地在常规临床SPECT成像工作流程中实施，并有可能提高诊断的可信度。该方法与预重建巴特沃斯滤波器有很大的潜力，以提高图像质量和定量精度的111In-SPECT图像。

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Impact of pre-reconstruction filtering with butterworth filter on 111In-pentetreotide SPECT image quality and quantitative accuracy: A phantom study

Introduction

This study evaluates the image quality and quantitative accuracy of SPECT images with pre- and post-reconstruction smoothing filters in somatostatin receptor scintigraphy using phantom data.

Methods

We evaluated the spatial resolution, the contrast-to-noise ratio (CNR), and the quantitative accuracy using a NEMA IEC body phantom filled with a ¹¹¹In solution. SPECT images were obtained with a Siemens Symbia T16 SPECT/CT system. Quantitative accuracy refers to the ability to accurately estimate the radioactive concentration of ¹¹¹In in the phantom from the image. SPECT reconstructions were performed using three methods: post-reconstruction Gaussian filtering (post-G), pre-reconstruction Gaussian filtering (pre-G), and pre-reconstruction Butterworth filtering (pre-B). To verify each filtering method, the cut-off frequency of the Butterworth filter and the full width at half maximum (FWHM) of the Gaussian filter were each changed to eight different settings.

Results

FWHMs were 21.2, 19.8, and 18.0 mm for post-G, pre-G, and pre-B. CNRs (37-mm sphere) were 47.2, 63.8, and 69.5. Pre-B showed a 12.0 % error rate at 0.40 cycles/cm, while post-G and pre-G showed 20.2 % and 22.0 % at 7.2-mm FWHM. Pre-B outperformed other methods for resolution, CNR, and quantitative accuracy.

Conclusion

For ¹¹¹In-pentetreotide SPECT images, image reconstruction with a Butterworth filter applied to the projection image before reconstruction was found to be superior to reconstruction with a Gaussian filter in terms of image quality and quantitative accuracy.

This method can be easily implemented in routine clinical SPECT imaging workflows and has the potential to improve diagnostic confidence.

Implications for practice

The proposed method with a pre-reconstruction Butterworth filter has great potential to improve the image quality and quantitative accuracy of ¹¹¹In-SPECT images.

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来源期刊

Radiography RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.70

自引率

34.60%

发文量

169

审稿时长

63 days

期刊介绍： Radiography is an International, English language, peer-reviewed journal of diagnostic imaging and radiation therapy. Radiography is the official professional journal of the College of Radiographers and is published quarterly. Radiography aims to publish the highest quality material, both clinical and scientific, on all aspects of diagnostic imaging and radiation therapy and oncology.