IF 1.7
4区 医学
Q3 GENETICS & HEREDITY
引用次数: 0
摘要
遗传密码是核苷酸序列与氨基酸相对应的一套规则。这些规则是由氨基酰基-tRNA合成酶（aaRSs）执行的，这种酶将氨基酸连接到tRNA分子上。这里有人认为，这种反应表明遗传密码可以被理解为一个“密码过程”。与流行的基于trna的遗传密码适配器模型相反，符号学模型识别由aars催化的“遗传密码过程”。本文章由计算机程序翻译，如有差异，请以英文原文为准。
Aminoacyl-tRNA synthetase: A ‘semiotic enzyme’
The genetic code is the set of rules by which nucleotide sequences correspond to amino acids. These rules are enforced by aminoacyl-tRNA synthetases (aaRSs): enzymes that ligate amino acids to tRNA molecules. Here it is argued this reaction suggests the genetic code may be understood as a ‘code process’. Contrary to the prevailing adaptor model of the genetic code based on tRNAs, the semiotic model recognises a ‘genetic code process’ catalysed by aaRSs.
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
193
审稿时长
66 days
期刊介绍：
The European Journal of Medical Genetics (EJMG) is a peer-reviewed journal that publishes articles in English on various aspects of human and medical genetics and of the genetics of experimental models.
Original clinical and experimental research articles, short clinical reports, review articles and letters to the editor are welcome on topics such as :
• Dysmorphology and syndrome delineation
• Molecular genetics and molecular cytogenetics of inherited disorders
• Clinical applications of genomics and nextgen sequencing technologies
• Syndromal cancer genetics
• Behavioral genetics
• Community genetics
• Fetal pathology and prenatal diagnosis
• Genetic counseling.
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