人类机器人的形态、行为和转录组生命周期（add . science . 31/2025）

IF 14.1 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-08-23 DOI:10.1002/advs.71198

Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio-Lopez, Douglas Hazel, Michael Levin

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引用次数: 0

摘要

这张封面捕捉到了一个“Anthrobot”，一个由单个成人气道上皮细胞生长而成的自我构建的多细胞球体。在没有基因工程或无机支架的情况下，人类机器人经历了不同的发育模式，展示了胚胎基因模式程序和系统发育上古老的转录组，自我修复，并实现了表观遗传返老返老-揭示了一种具有自己生命周期和动态行为的新型生命结构。更多细节可以在Gizem Gumuskaya， Michael Levin及其同事的文章编号2409330中找到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots (Adv. Sci. 31/2025)

查看原文本刊更多论文

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots (Adv. Sci. 31/2025)

Anthrobots

This cover captures an “Anthrobot,” a self-constructing multicellular spheroid grown from a single adult human airway epithelial cell. Without genetic engineering or inorganic scaffolds, Anthrobots undergo distinct developmental modes, display embryonic gene-patterning programs and a phylogenetically ancient transcriptome, self-repair, and achieve epigenetic rejuvenation–revealing a novel living architecture with its own life cycle and dynamic behaviors. More details can be found in article number 2409330 by Gizem Gumuskaya, Michael Levin, and co-workers.

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.