机械力通过黑质纹状体途径引导轴突生长的器官型模型（Adv. science . 31/2025）

IF 14.1 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-08-23 DOI:10.1002/advs.71197

Sara De Vincentiis, Elena Capitanini, Karen Kira, Claudia Dell'Amico, Jun Takahashi, Marco Onorati, Fabian Raudzus, Vittoria Raffa

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引用次数: 0

摘要

在文章编号2500400中，victoria Raffa， Fabian Raudzus及其同事提出了一种重建器官型帕金森模型神经网络的新方法。利用一种被称为纳米牵引的技术，磁力被应用于引导装载纳米粒子的人类皮层神经和ipsc衍生的多巴胺能祖细胞的轴突生长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model (Adv. Sci. 31/2025)

查看原文本刊更多论文

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model (Adv. Sci. 31/2025)

Reconstruct Neural Networks

In article number 2500400, Vittoria Raffa, Fabian Raudzus, and co-workers present a novel approach to reconstruct neural networks in an organotypic Parkinson's model. Using a technique called nano-pulling, magnetic forces are applied to guide axonal growth of nanoparticle-loaded human cortical neural and iPSC-derived dopaminergic progenitors.

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.