巴西南部自然感染犬体内的重要Rangelia:疾病分为急性期和亚急性期的临床分类

IF 1.4 Q3 PARASITOLOGY
Felipe Carniel , Gustavo Willian Pandolfo , Paulo E. Ferian , Julieta Volpato , Maysa Garlet Nunes Xavier , Mariângela Lovatel , Marília Luciani , Eloiza Zoboli , João Fabio Soares , Renata Assis Casagrande
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引用次数: 0

摘要

犬rangelosis是一种血管外溶血性疾病,由重要的Rangelia vitalii引起。本研究旨在建立疾病的临床分类,分为急性期和亚急性期,并描述自然感染犬的临床、血液学和病理结果。选取18只犬,进行全血细胞计数、血清生化、耳缘血涂片、腹部超声检查、活体R. R.和巴贝斯虫聚合酶链反应,并对3只犬进行尸检。在急性期最一致的表现包括血小板减少、巨噬细胞增多、豪威尔-乔利体、粗性低回声脾肿大、高热和心动过速。在亚急性期,表现包括中度血小板减少、大血小板、细胞异位和多色症、贫血、粗性低回声脾肿大、低蛋白血症和低白蛋白血症、尿γ -谷氨酰转移酶水平升高、嗜睡和厌食。血小板减少和脾肿大是最常见的改变,出现在所有病例中。在血液涂片中,61.1%的病例以游离形式存在原虫。病理表现为血管外溶血性疾病的特征,以肠、心脏、胰腺和膀胱的组织寄生最为严重。本研究描述了rangeliosis的临床特征,强调将该疾病分为急性期和亚急性期。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rangelia vitalii in naturally infected dogs in southern Brazil: clinical classification of the disease into acute and subacute phases
Canine rangeliosis, caused by Rangelia vitalii, is an extravascular hemolytic disease. This study aimed to establish a clinical classification of the disease into acute and subacute phases and to describe the clinical, hematological, and pathological findings in naturally infected dogs. Eighteen dogs were included and submitted a complete blood count, serum biochemistry, ear margin blood smear, abdominal ultrasonography, polymerase chain reaction for R. vitalii and Babesia spp., and three dogs were necropsied. All animals were positive for R. vitalii and negative for Babesia spp. The most consistent findings in the acute phase included thrombocytopenia, macrocytosis, Howell-Jolly bodies, coarse hypoechoic splenomegaly, hyperthermia, and tachycardia. In the subacute phase, findings included moderate thrombocytopenia, macrothrombocytes, anisocytosis, and polychromasia, anemia, coarse hypoechoic splenomegaly, hypoproteinemia and hypoalbuminemia, increased urinary gamma-glutamyl transferase levels, lethargy, and anorexia. Thrombocytopenia and splenomegaly were the most frequent alterations, present in all cases. In blood smears, the protozoan was in its free form in 61.1 % of cases. The pathological findings were characteristic of extravascular hemolytic disease, with the most severe tissue parasitism was observed in the intestine, heart, pancreas, and bladder. This study to describe the clinical features of rangeliosis, emphasizing a clinical classification of the disease into to acute and subacute phases.
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来源期刊
CiteScore
2.90
自引率
7.10%
发文量
126
审稿时长
97 days
期刊介绍: Veterinary Parasitology: Regional Studies and Reports focuses on aspects of veterinary parasitology that are of regional concern, which is especially important in this era of climate change and the rapid and often unconstrained travel of people and animals. Relative to regions, this journal will accept papers of the highest quality dealing with all aspects of disease prevention, pathology, treatment, epidemiology, and control of parasites within the field of veterinary medicine. Also, case reports will be considered as they add to information related to local disease and its control; such papers must be concise and represent appropriate medical intervention. Papers on veterinary parasitology from wildlife species are acceptable, but only if they relate to the practice of veterinary medicine. Studies on vector-borne bacterial and viral agents are suitable, but only if the paper deals with vector transmission of these organisms to domesticated animals. Studies dealing with parasite control by means of natural products, both in vivo and in vitro, are more suited for one of the many journals that now specialize in papers of this type. However, due to the regional nature of much of this research, submissions may be considered based upon a case being made by the author(s) to the Editor. Circumstances relating to animal experimentation must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for International Organizations of Medical Sciences (obtainable from: Executive Secretary C.I.O.M.S., c/o W.H.O., Via Appia, CH-1211 Geneva 27, Switzerland).
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