Jan Bociański , Katarzyna Sklinda , Jerzy Walecki , Wojciech Rogowski , Michał Małek , Marek Kasprowicz , Łukasz Michałowski , Weronika Popow
{"title":"高级别前列腺癌伴低PSA水平1例","authors":"Jan Bociański , Katarzyna Sklinda , Jerzy Walecki , Wojciech Rogowski , Michał Małek , Marek Kasprowicz , Łukasz Michałowski , Weronika Popow","doi":"10.1016/j.eucr.2025.103161","DOIUrl":null,"url":null,"abstract":"<div><div>Prostate-specific antigen (PSA) levels typically correlate with the risk of prostate cancer. However, it is uncommon for an extensive malignant infiltration to occur with persistently low PSA levels. We present a case of a young male with a large tumor originating from the transition zone of the prostate and with low PSA levels This case underscores the biological heterogeneity of prostate cancer and suggests that tumors arising in the transition zone may differ significantly in behavior from those originating in the peripheral zone.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"62 ","pages":"Article 103161"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of high-grade prostate cancer with low PSA levels\",\"authors\":\"Jan Bociański , Katarzyna Sklinda , Jerzy Walecki , Wojciech Rogowski , Michał Małek , Marek Kasprowicz , Łukasz Michałowski , Weronika Popow\",\"doi\":\"10.1016/j.eucr.2025.103161\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Prostate-specific antigen (PSA) levels typically correlate with the risk of prostate cancer. However, it is uncommon for an extensive malignant infiltration to occur with persistently low PSA levels. We present a case of a young male with a large tumor originating from the transition zone of the prostate and with low PSA levels This case underscores the biological heterogeneity of prostate cancer and suggests that tumors arising in the transition zone may differ significantly in behavior from those originating in the peripheral zone.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"62 \",\"pages\":\"Article 103161\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-08-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025002323\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025002323","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
A case of high-grade prostate cancer with low PSA levels
Prostate-specific antigen (PSA) levels typically correlate with the risk of prostate cancer. However, it is uncommon for an extensive malignant infiltration to occur with persistently low PSA levels. We present a case of a young male with a large tumor originating from the transition zone of the prostate and with low PSA levels This case underscores the biological heterogeneity of prostate cancer and suggests that tumors arising in the transition zone may differ significantly in behavior from those originating in the peripheral zone.