包裹技术治疗特发性三叉神经痛:患者系列。

Sophie Jia Qian Koh, A Aravin Kumar, Peter Ying Khai Hwang
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引用次数: 0

摘要

背景:特发性三叉神经痛(TN)提出了重大的诊断和治疗挑战。虽然微血管减压(MVD)在经典TN中的作用已经确立,但由于缺乏可识别的神经血管冲突和缺乏明确的解剖靶点,其在特发性病例中的作用仍存在争议。需要新的策略来应对这一具有挑战性的患者群体。观察:6例特发性TN患者行三叉神经周围聚四氟乙烯包裹MVD。所有患者均接受了高分辨率MRI (CISS或FIESTA序列),术中探查未发现神经血管冲突。术中三叉-舌下反射(THR)监测作为减压的功能标记。所有患者在基线时均表现出完整的THR,在包裹置放后THR完全消失,表明充分的减压。术前Barrow Neurological Institute疼痛评分(BNI-PS)从III到v不等,5例患者在术后第1天达到持续疼痛缓解(BNI-PS为0或I)。1例患者出现延迟改善,但在6个月时从BNI-PS IV进展到0。所有患者在18个月时均无疼痛。经验:Teflon包膜技术与术中THR监测可能是特发性TN的一种安全有效的手术选择。通过解决潜在的生物力学或动态神经功能障碍,这种方法即使在没有明显血管冲突的情况下也能有效缓解疼痛。https://thejns.org/doi/10.3171/CASE25348。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Wrap technique for idiopathic trigeminal neuralgia: patient series.

Wrap technique for idiopathic trigeminal neuralgia: patient series.

Background: Idiopathic trigeminal neuralgia (TN) presents significant diagnostic and therapeutic challenges. While microvascular decompression (MVD) is well established for classic TN, its role in idiopathic cases remains controversial due to the absence of an identifiable neurovascular conflict and lack of clear anatomical target. New strategies are needed to address this challenging patient population.

Observations: Six patients with idiopathic TN underwent MVD with a Teflon wrap placed around the trigeminal nerve. All had undergone high-resolution MRI (CISS or FIESTA sequence), and intraoperative exploration was negative for a neurovascular conflict. Intraoperative trigeminal-hypoglossal reflex (THR) monitoring was used as a functional marker of decompression. All patients exhibited intact THR at baseline and complete loss of THR after wrap placement, indicating adequate decompression. Preoperative Barrow Neurological Institute pain scores (BNI-PSs) ranged from III to V. Five patients achieved sustained pain relief (BNI-PS of 0 or I) by postoperative day 1. One patient experienced delayed improvement but progressed from BNI-PS IV to 0 by 6 months. All patients remained pain free at 18 months.

Lessons: A Teflon wrap technique with intraoperative THR monitoring may represent a safe and effective surgical option for idiopathic TN. By addressing potential biomechanical or dynamic nerve dysfunction, this approach offers meaningful pain relief even in the absence of a visible vascular conflict. https://thejns.org/doi/10.3171/CASE25348.

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