心脏手术中的右胸膜-心包窗:一种安全、简单的减少术后心房颤动的技术。

IF 1.3
Nadine Kawkabani, Rita Farah, Joseph Akar, Wael Daajeh, Mohammad Mokdad, Moussa Abi Ghanem, Bassam Abi Khalil
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引用次数: 0

摘要

目的:术后心房颤动(POAF)是心脏手术后常见的并发症,与住院时间、发病率和死亡率增加有关。诱发POAF的主要因素之一是心包积液相关的炎症,这可能发生在心脏手术后。我们假设,通过在心脏手术中关闭胸部之前创建一个胸膜-心包窗,将心包空间引流到右侧胸膜空间可能会减少心包积液和术后房颤。方法:我们进行了一项研究,包括172例连续接受心脏手术的患者(67±12岁,48.3%女性)(73.8%主动脉瓣置换术[AVR], 5.8%二尖瓣置换术,19% AVR +冠状动脉旁路移植术)。本研究纳入的前95例患者(67±12岁,48%女性)没有创建任何胸膜-心包窗,而其余77例患者(67±12岁,48%女性)创建了胸膜-心包窗。比较两组患者的基线临床和手术特征。收集术后事件和并发症直至出院。结果:共有50例患者发生POAF(29%)。经胸膜-心包窗手术的患者中POAF的发生率为18.2%(95%可信区间[CI]: 9.4%-27.0%)。采用标准技术的患者POAF发生率为37.7% (95% CI: 28.0%-47.8%)。行胸膜-心包窗的患者血脂异常(p = 0.037)、右束支传导阻滞(p = 0.018)、1度房室传导阻滞(p = 0.046)和既往心肌梗死(p = 0.006)的发生率较高。多因素分析显示,与未行胸膜-心包窗术的患者相比,行胸膜-心包窗术的患者发生POAF的风险显著降低(优势比:0.46,95% CI: 0.24-0.87, p = 0.019)。结论:心脏手术后关闭胸部前建立右胸膜-心包窗与较低的POAF发生率独立相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Right Pleuro-Pericardial Window during Cardiac Surgery: A Safe and Simple Technique that Decreases Postoperative Atrial Fibrillation.

Purpose: Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery and is associated with increased hospital stay, morbidity, and mortality. One of the major factors predisposing patients to the development of POAF is inflammation related to pericardial effusions, which may occur after cardiac surgery. We hypothesized that by creating a pleuro-pericardial window before closing the chest during cardiac surgery, draining the pericardial space into the right pleural space may lead to fewer pericardial effusions and less postoperative atrial fibrillation.

Methods: We conducted a study that included 172 consecutive patients (67 ± 12 years, 48.3% female) who underwent cardiac surgery (73.8% aortic valve replacement [AVR], 5.8% mitral valve replacement, 19% AVR + coronary artery bypass grafting). The first 95 patients included in this study (67 ± 12 years, 48% female) did not have any pleuro-pericardial window created, whereas the remaining 77 patients (67 ± 12 years, 48% female) did. Baseline clinical and procedural characteristics were compared between the 2 groups. Postoperative events and complications were collected until hospital discharge.

Results: A total of 50 patients developed POAF (29%). The incidence of POAF among patients who underwent a pleuro-pericardial window was 18.2% (95% confidence interval [CI]: 9.4%-27.0%). The incidence of POAF among those who underwent the standard technique was 37.7% (95% CI: 28.0%-47.8%). The patients who underwent a pleuro-pericardial window had a higher incidence of dyslipidemia (p = 0.037), right bundle branch block (p = 0.018), 1st-degree atrioventricular block (p = 0.046), and previous myocardial infarction (p = 0.006). Multivariate analysis showed that the risk of POAF was significantly lower in patients who underwent a pleuro-pericardial window compared to those who did not (odds ratio: 0.46, 95% CI: 0.24-0.87, p = 0.019).

Conclusion: Creating a right pleuro-pericardial window before closing the chest after cardiac surgery was independently associated with a lower incidence of POAF.

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