{"title":"【仁都通条针刺治疗肾阴虚火亢型多囊卵巢综合征雄激素分泌过多的疗效观察】。","authors":"Yuane Liu, Baidan Liao, Xian Zhang, Chang Zhou, Chen Chen","doi":"10.13703/j.0255-2930.20240612-0003","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical therapeutic effect of <i>Rendu Tongtiao</i> acupuncture (acupuncture for regulating and improving the circulation of the conception and governor vessels) on hyperandrogenism (HA) in polycystic ovary syndrome (PCOS) with kidney-<i>yin</i> deficiency induced fire hyperactivity.</p><p><strong>Methods: </strong>A total of 80 PCOS-HA patients were selected and randomly divided into an observation group and a control group, 40 cases in each group. In the control group, ethinylestradiol and cyproterone acetate tablets were administered orally,2 mg each time, once daily and for 21 consecutive days as one menstrual cycle. In the observation group, <i>Rendu Tongtiao</i> acupuncture was delivered at Qihai (CV6), Zhongwan (CV12), Guanyuan (CV4), Zhongji (CV3), Mingmen (GV4), Yaoyangguan (GV3), etc. once daily till ovulation, which was taken as the treatment session of one menstrual cycle. The treatment was completed after 3 menstrual cycles in each group. Before and after treatment, the serum levels of testosterone (T), dihydrotestosterone (DHT), luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), sex hormone-binding globulin (SHBG), and the scores of acne and hirsutism were compared in the two groups; besides, menstrual recovery rate, ovulation recovery rate, basic body temperature (BBT) biphasic rate and clinical effect were compared between the two groups.</p><p><strong>Results: </strong>Compared with those before treatment, the levels of T, DHT, LH and PRL, as well as the scores of acne and hirsutism were reduced in the two groups after treatment (<i>P</i><0.05), and the levels of FSH and SHBG were increased (<i>P</i><0.05). After treatment, the levels of T, DHT, LH and PRL, as well as the scores of acne and hirsutism in the observation group were lower than those in the control group (<i>P</i><0.05); and FSH and SHBG were higher (<i>P</i><0.05). After treatment, the menstrual recovery rate and ovulation recovery rate, as well as BBT biphasic rate in the observation group increased in comparison with the control group (<i>P</i><0.05). The total effective rate was 97.5% (39/40) in the observation group, which was higher than 82.4% (33/40) of the control group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong><i>Rendu Tongtiao</i> acupuncture can effectively regulate the secretion of hormones, alleviate the clinical symptoms of HA, and accelerate the recovery of menstruation and natural ovulation in patients with PCOS-HA of kidney-<i>yin</i> deficiency induced fire hyperactivity .</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1078-1082"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Therapeutic effect of <i>Rendu Tongtiao</i> acupuncture on hyperandrogenism in polycystic ovary syndrome of kidney-<i>yin</i> deficiency induced fire hyperactivity].\",\"authors\":\"Yuane Liu, Baidan Liao, Xian Zhang, Chang Zhou, Chen Chen\",\"doi\":\"10.13703/j.0255-2930.20240612-0003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To investigate the clinical therapeutic effect of <i>Rendu Tongtiao</i> acupuncture (acupuncture for regulating and improving the circulation of the conception and governor vessels) on hyperandrogenism (HA) in polycystic ovary syndrome (PCOS) with kidney-<i>yin</i> deficiency induced fire hyperactivity.</p><p><strong>Methods: </strong>A total of 80 PCOS-HA patients were selected and randomly divided into an observation group and a control group, 40 cases in each group. In the control group, ethinylestradiol and cyproterone acetate tablets were administered orally,2 mg each time, once daily and for 21 consecutive days as one menstrual cycle. In the observation group, <i>Rendu Tongtiao</i> acupuncture was delivered at Qihai (CV6), Zhongwan (CV12), Guanyuan (CV4), Zhongji (CV3), Mingmen (GV4), Yaoyangguan (GV3), etc. once daily till ovulation, which was taken as the treatment session of one menstrual cycle. The treatment was completed after 3 menstrual cycles in each group. Before and after treatment, the serum levels of testosterone (T), dihydrotestosterone (DHT), luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), sex hormone-binding globulin (SHBG), and the scores of acne and hirsutism were compared in the two groups; besides, menstrual recovery rate, ovulation recovery rate, basic body temperature (BBT) biphasic rate and clinical effect were compared between the two groups.</p><p><strong>Results: </strong>Compared with those before treatment, the levels of T, DHT, LH and PRL, as well as the scores of acne and hirsutism were reduced in the two groups after treatment (<i>P</i><0.05), and the levels of FSH and SHBG were increased (<i>P</i><0.05). After treatment, the levels of T, DHT, LH and PRL, as well as the scores of acne and hirsutism in the observation group were lower than those in the control group (<i>P</i><0.05); and FSH and SHBG were higher (<i>P</i><0.05). After treatment, the menstrual recovery rate and ovulation recovery rate, as well as BBT biphasic rate in the observation group increased in comparison with the control group (<i>P</i><0.05). The total effective rate was 97.5% (39/40) in the observation group, which was higher than 82.4% (33/40) of the control group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong><i>Rendu Tongtiao</i> acupuncture can effectively regulate the secretion of hormones, alleviate the clinical symptoms of HA, and accelerate the recovery of menstruation and natural ovulation in patients with PCOS-HA of kidney-<i>yin</i> deficiency induced fire hyperactivity .</p>\",\"PeriodicalId\":69903,\"journal\":{\"name\":\"中国针灸\",\"volume\":\"45 8\",\"pages\":\"1078-1082\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国针灸\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.13703/j.0255-2930.20240612-0003\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国针灸","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.13703/j.0255-2930.20240612-0003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/30 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
[Therapeutic effect of Rendu Tongtiao acupuncture on hyperandrogenism in polycystic ovary syndrome of kidney-yin deficiency induced fire hyperactivity].
Objective: To investigate the clinical therapeutic effect of Rendu Tongtiao acupuncture (acupuncture for regulating and improving the circulation of the conception and governor vessels) on hyperandrogenism (HA) in polycystic ovary syndrome (PCOS) with kidney-yin deficiency induced fire hyperactivity.
Methods: A total of 80 PCOS-HA patients were selected and randomly divided into an observation group and a control group, 40 cases in each group. In the control group, ethinylestradiol and cyproterone acetate tablets were administered orally,2 mg each time, once daily and for 21 consecutive days as one menstrual cycle. In the observation group, Rendu Tongtiao acupuncture was delivered at Qihai (CV6), Zhongwan (CV12), Guanyuan (CV4), Zhongji (CV3), Mingmen (GV4), Yaoyangguan (GV3), etc. once daily till ovulation, which was taken as the treatment session of one menstrual cycle. The treatment was completed after 3 menstrual cycles in each group. Before and after treatment, the serum levels of testosterone (T), dihydrotestosterone (DHT), luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), sex hormone-binding globulin (SHBG), and the scores of acne and hirsutism were compared in the two groups; besides, menstrual recovery rate, ovulation recovery rate, basic body temperature (BBT) biphasic rate and clinical effect were compared between the two groups.
Results: Compared with those before treatment, the levels of T, DHT, LH and PRL, as well as the scores of acne and hirsutism were reduced in the two groups after treatment (P<0.05), and the levels of FSH and SHBG were increased (P<0.05). After treatment, the levels of T, DHT, LH and PRL, as well as the scores of acne and hirsutism in the observation group were lower than those in the control group (P<0.05); and FSH and SHBG were higher (P<0.05). After treatment, the menstrual recovery rate and ovulation recovery rate, as well as BBT biphasic rate in the observation group increased in comparison with the control group (P<0.05). The total effective rate was 97.5% (39/40) in the observation group, which was higher than 82.4% (33/40) of the control group (P<0.05).
Conclusion: Rendu Tongtiao acupuncture can effectively regulate the secretion of hormones, alleviate the clinical symptoms of HA, and accelerate the recovery of menstruation and natural ovulation in patients with PCOS-HA of kidney-yin deficiency induced fire hyperactivity .
期刊介绍：
Chinese Acupuncture and Moxibustion (founded in 1981, monthly) is an authoritative academic journal of acupuncture and moxibustion under the supervision of China Association for Science and Technology and co-sponsored by Chinese Acupuncture and Moxibustion Society and Institute of Acupuncture and Moxibustion of China Academy of Traditional Chinese Medicine. It is recognised as a core journal of Chinese science and technology, a core journal of Chinese language, and is included in the core journals of China Science Citation Database, as well as being included in MEDLINE and other international well-known medical index databases. The journal adheres to the tenet of ‘improving, taking into account the popularity, colourful and realistic’, and provides valuable learning and communication opportunities for the majority of acupuncture and moxibustion clinical and scientific research workers, and plays an important role in the domestic and international publicity and promotion of acupuncture and moxibustion disciplines.
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