解码高阶网络互动如何塑造传染动力学。

IF 2.3 4区 数学 Q2 BIOLOGY
István Z Kiss, Christian Bick, Péter L Simon
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引用次数: 0

摘要

涉及沿高阶结构(如简单复合体和超图)传染的复杂传染模型产生了新类别的平均场模型。有趣的是,从许多这样的模型中产生的微分方程往往表现出类似的形式,导致质量上可比较的全球分岔模式。在这种观察的激励下,我们研究了一个广义的平均场型模型,该模型为分析一系列不同的模型提供了一个统一的框架。特别地,我们导出了三种复杂性不断增加的模型所表现出的不同分岔状态出现的分析条件——从三体和四体相互作用到同时包括两体和三体相互作用的两个连接种群。对于前两种情况,我们给出了所有可能结果的完整特征,以及相应的网络和流行病参数条件。在第三种情况下,我们证明了多稳定性是可能的,尽管只有三体相互作用。我们的研究结果表明,具有三体相互作用的单种群模型只能表现出简单的跨临界转变或双稳态,而具有四体相互作用的多稳态模型可能具有两个不同的地方性稳态。令人惊讶的是,尽管只有三体相互作用,双种群模型通过对称破缺表现出多稳定性。我们的工作揭示了方程结构和模型行为之间的关系,并向阐明不同系统行为产生的机制,以及网络和动态特性如何促进或阻碍结果迈出了第一步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Decoding how higher-order network interactions shape contagion dynamics.

Decoding how higher-order network interactions shape contagion dynamics.

Decoding how higher-order network interactions shape contagion dynamics.

Decoding how higher-order network interactions shape contagion dynamics.

Complex contagion models that involve contagion along higher-order structures, such as simplicial complexes and hypergraphs, yield new classes of mean-field models. Interestingly, the differential equations arising from many such models often exhibit a similar form, resulting in qualitatively comparable global bifurcation patterns. Motivated by this observation, we investigate a generalised mean-field-type model that provides a unified framework for analysing a range of different models. In particular, we derive analytical conditions for the emergence of different bifurcation regimes exhibited by three models of increasing complexity-ranging from three- and four-body interactions to two connected populations which simultaneously includes both pairwise and three-body interactions. For the first two cases, we give a complete characterisation of all possible outcomes, along with the corresponding conditions on network and epidemic parameters. In the third case, we demonstrate that multistability is possible despite only three-body interactions. Our results reveal that single population models with three-body interactions can only exhibit simple transcritical transitions or bistability, whereas with four-body interactions multistability with two distinct endemic steady states is possible. Surprisingly, the two-population model exhibits multistability via symmetry breaking despite three-body interactions only. Our work sheds light on the relationship between equation structure and model behaviour and makes the first step towards elucidating mechanisms by which different system behaviours arise, and how network and dynamic properties facilitate or hinder outcomes.

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来源期刊
CiteScore
3.30
自引率
5.30%
发文量
120
审稿时长
6 months
期刊介绍: The Journal of Mathematical Biology focuses on mathematical biology - work that uses mathematical approaches to gain biological understanding or explain biological phenomena. Areas of biology covered include, but are not restricted to, cell biology, physiology, development, neurobiology, genetics and population genetics, population biology, ecology, behavioural biology, evolution, epidemiology, immunology, molecular biology, biofluids, DNA and protein structure and function. All mathematical approaches including computational and visualization approaches are appropriate.
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