坚持协议-诊断的逻辑-致敬e.m.尼科尔斯（1927-2011）。

IF 1.2 4区医学 Q4 GENETICS & HEREDITY

Twin Research and Human Genetics Pub Date : 2025-08-19 DOI:10.1017/thg.2025.10017

Alan E Stark, Paulo A Otto

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引用次数: 0

摘要

马克斯·尼科尔斯作为一名医学从业者、研究人员和医学遗传学教师，有着几乎独一无二的经历。一篇较早的论文描述了他对神经纤维瘤病病因学的贡献。接下来是Nicholls自己在澳大利亚新南威尔士大学医学院担任讲师的经历。这篇笔记使人们注意到他在免疫学方面的研究。例如，他在白皮毛白细胞凝集（BCLA）试验的研究中发挥了重要作用，这是一种检测细胞介导免疫的敏感试验，他引入了这种试验来检测临床前阶段的疾病（包括癌症）。

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Upholding Protocol - The Logic of Diagnosis - Tribute to E. M. Nicholls (1927-2011).

Max Nicholls had an almost unique experience as a medical practitioner, researcher and teacher of medical genetics. An earlier paper described his contribution to the etiology of neurofibromatosis. This was followed by Nicholls' own experience as lecturer in the Faculty of Medicine, University of New South Wales, Australia. This note draws attention to his research in immunology. For example, he was instrumental in the study of the buffy coat leuko-agglutination (BCLA) test, a sensitive assay for cell-mediated immunity that he introduced to detect conditions (including cancer) in preclinical stages.

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来源期刊

Twin Research and Human Genetics 医学-妇产科学

CiteScore

1.50

自引率

11.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.