{"title":"Lenke 1型和2型青少年特发性脊柱侧凸术后远端附加现象进展的危险因素","authors":"Tao Li, Yong Li, Xiangbin Wang, Yubin Long","doi":"10.1038/s41598-025-15714-1","DOIUrl":null,"url":null,"abstract":"<p><p>To investigate risk factors associated with the progression of the distal adding-on phenomenon after posterior selective thoracic fusion in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis (AIS). A retrospective analysis was conducted on 152 patients who underwent posterior selective thoracic fusion from December 2015 to December 2021. Among them, 48 patients experienced the distal adding-on phenomenon postoperatively. Based on whether this phenomenon progressed during follow-up, they were divided into progressive and non-progressive groups. Univariate analysis compared clinical and imaging data between the two groups, while multivariate logistic regression identified independent risk factors. Of the 48 patients with postoperative distal adding-on, 37 (77.1%) were non-progressive and 11 (22.9%) were progressive. Univariate analysis showed significant differences between the progressive and non-progressive groups in Risser sign grade (2.27 ± 1.10 vs. 3.73 ± 0.87, P < 0.001), number of segments between lowest instrumented vertebra (LIV) and the last substantially touched vertebra (LSTV) (-1.27 ± 0.79 vs. 0.51 ± 1.17, P < 0.001), preoperative clavicle angle (-2.55 ± 2.84 vs. -0.11 ± 2.82, P = 0.015), and preoperative trunk shift (21.05 ± 15.27 vs. 10.46 ± 13.32, P = 0.030). Multivariate analysis confirmed that lower Risser sign grade (OR = 0.16, 95% CI 0.03-0.82, P = 0.028) and fewer segments between LIV and LSTV (OR = 0.07, 95% CI 0.01-0.58, P = 0.013) were independent risk factors for the progression of the distal adding-on phenomenon. Lower skeletal maturity (Risser sign grade) and LIV located cephalad to LSTV are independent risk factors for the progression of the distal adding-on phenomenon in patients with Lenke type 1 and 2 AIS. For skeletally immature patients (Risser ≤ 3), LSTV should be preferentially chosen as LIV during surgery.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"30237"},"PeriodicalIF":3.9000,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361458/pdf/","citationCount":"0","resultStr":"{\"title\":\"Risk factors for the progression of distal adding-on phenomenon after surgery in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis.\",\"authors\":\"Tao Li, Yong Li, Xiangbin Wang, Yubin Long\",\"doi\":\"10.1038/s41598-025-15714-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>To investigate risk factors associated with the progression of the distal adding-on phenomenon after posterior selective thoracic fusion in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis (AIS). A retrospective analysis was conducted on 152 patients who underwent posterior selective thoracic fusion from December 2015 to December 2021. Among them, 48 patients experienced the distal adding-on phenomenon postoperatively. Based on whether this phenomenon progressed during follow-up, they were divided into progressive and non-progressive groups. Univariate analysis compared clinical and imaging data between the two groups, while multivariate logistic regression identified independent risk factors. Of the 48 patients with postoperative distal adding-on, 37 (77.1%) were non-progressive and 11 (22.9%) were progressive. Univariate analysis showed significant differences between the progressive and non-progressive groups in Risser sign grade (2.27 ± 1.10 vs. 3.73 ± 0.87, P < 0.001), number of segments between lowest instrumented vertebra (LIV) and the last substantially touched vertebra (LSTV) (-1.27 ± 0.79 vs. 0.51 ± 1.17, P < 0.001), preoperative clavicle angle (-2.55 ± 2.84 vs. -0.11 ± 2.82, P = 0.015), and preoperative trunk shift (21.05 ± 15.27 vs. 10.46 ± 13.32, P = 0.030). Multivariate analysis confirmed that lower Risser sign grade (OR = 0.16, 95% CI 0.03-0.82, P = 0.028) and fewer segments between LIV and LSTV (OR = 0.07, 95% CI 0.01-0.58, P = 0.013) were independent risk factors for the progression of the distal adding-on phenomenon. Lower skeletal maturity (Risser sign grade) and LIV located cephalad to LSTV are independent risk factors for the progression of the distal adding-on phenomenon in patients with Lenke type 1 and 2 AIS. For skeletally immature patients (Risser ≤ 3), LSTV should be preferentially chosen as LIV during surgery.</p>\",\"PeriodicalId\":21811,\"journal\":{\"name\":\"Scientific Reports\",\"volume\":\"15 1\",\"pages\":\"30237\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361458/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Scientific Reports\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://doi.org/10.1038/s41598-025-15714-1\",\"RegionNum\":2,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scientific Reports","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1038/s41598-025-15714-1","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Risk factors for the progression of distal adding-on phenomenon after surgery in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis.
To investigate risk factors associated with the progression of the distal adding-on phenomenon after posterior selective thoracic fusion in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis (AIS). A retrospective analysis was conducted on 152 patients who underwent posterior selective thoracic fusion from December 2015 to December 2021. Among them, 48 patients experienced the distal adding-on phenomenon postoperatively. Based on whether this phenomenon progressed during follow-up, they were divided into progressive and non-progressive groups. Univariate analysis compared clinical and imaging data between the two groups, while multivariate logistic regression identified independent risk factors. Of the 48 patients with postoperative distal adding-on, 37 (77.1%) were non-progressive and 11 (22.9%) were progressive. Univariate analysis showed significant differences between the progressive and non-progressive groups in Risser sign grade (2.27 ± 1.10 vs. 3.73 ± 0.87, P < 0.001), number of segments between lowest instrumented vertebra (LIV) and the last substantially touched vertebra (LSTV) (-1.27 ± 0.79 vs. 0.51 ± 1.17, P < 0.001), preoperative clavicle angle (-2.55 ± 2.84 vs. -0.11 ± 2.82, P = 0.015), and preoperative trunk shift (21.05 ± 15.27 vs. 10.46 ± 13.32, P = 0.030). Multivariate analysis confirmed that lower Risser sign grade (OR = 0.16, 95% CI 0.03-0.82, P = 0.028) and fewer segments between LIV and LSTV (OR = 0.07, 95% CI 0.01-0.58, P = 0.013) were independent risk factors for the progression of the distal adding-on phenomenon. Lower skeletal maturity (Risser sign grade) and LIV located cephalad to LSTV are independent risk factors for the progression of the distal adding-on phenomenon in patients with Lenke type 1 and 2 AIS. For skeletally immature patients (Risser ≤ 3), LSTV should be preferentially chosen as LIV during surgery.
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