冠心病患者一级亲属传统冠心病危险因素的性别特征及QRISK3评分的比较分析

IF 1.4 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Meena Parmar, Pooja Vyas, Krutika Patel, Atisha Rana, Vijay Kalsariya, Mayuri Zadafiya
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引用次数: 0

摘要

背景:冠状动脉疾病(CAD)是全球死亡的主要原因,遗传和生活方式因素有助于其发展。由于共同的遗传和环境,冠心病患者的一级亲属风险增加。本研究旨在对CAD患者一级亲属中传统CAD危险因素和QRISK3评分的性别差异模式进行比较分析。研究设计:横断面研究。方法:本研究招募了4485名因冠心病住院患者的一级亲属。对冠心病一级亲属进行性别比较,评估传统危险因素和QRISK3评分。结果:患者的平均年龄为41.8岁,男性占我们研究参与者的66%。男性表现出更多的传统危险因素,包括较高的收缩压和舒张压、血脂异常、吸烟、饮酒、垃圾食品消费和口服烟草使用。女性肥胖、睡眠不足、抑郁和偏头痛的患病率更高。根据QRISK3评分,男性10年CAD风险显著增加,反映出健康心脏年龄比实足年龄增加4.20±1.32岁(P=0.0004)。结论:已知冠心病患者的一级男性亲属冠脉危险因素的患病率是女性的两倍。在危险因素和QRISK3评分中发现了明显的性别差异,突出了在这一高危人群中评估和管理CAD风险的特定方法的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Comparative Analysis of Gender-Specific Patterns of Traditional Coronary Artery Disease Risk Factors and QRISK3 Scores in First-Degree Relatives of Coronary Artery Disease Patients.

Comparative Analysis of Gender-Specific Patterns of Traditional Coronary Artery Disease Risk Factors and QRISK3 Scores in First-Degree Relatives of Coronary Artery Disease Patients.

Background: Coronary artery disease (CAD) is a leading cause of death globally, with genetic and lifestyle factors contributing to its development. The first-degree relatives of CAD patients are at increased risk due to shared genetics and environments. This study aimed to perform a comparative analysis of gender-specific patterns of traditional CAD risk factors and QRISK3 scores in the first-degree relatives of CAD patients. Study Design: A cross-sectional study.

Methods: This study enrolled 4,485 participants of first-degree relatives of patients who had been admitted to the hospital for CAD. Gender-specific comparisons were conducted in the first-degree relatives of CAD to assess traditional risk factors and QRISK3 scores.

Results: The mean age of patients was 41.8 years, with males comprising 66% of participants in our study. Males exhibited more traditional risk factors, including higher systolic and diastolic blood pressure, dyslipidaemia, smoking, alcohol, junk food consumption, and oral tobacco use. Females had a higher prevalence of obesity, inadequate sleep, depression, and migraines. Males had a significantly higher 10-year CAD risk according to QRISK3 scores, reflecting an increased healthy heart age of 4.20±1.32 years compared to their chronological age (P=0.0004).

Conclusion: The prevalence of coronary risk factors was twice as high in the first-degree male relatives of individuals with known CAD compared to females. Distinct gender-based differences were found in risk factors and QRISK3 scores, highlighting the significance of specific approaches in evaluating and managing the risk of CAD within this high-risk group.

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来源期刊
Journal of research in health sciences
Journal of research in health sciences PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.30
自引率
13.30%
发文量
7
期刊介绍: The Journal of Research in Health Sciences (JRHS) is the official journal of the School of Public Health; Hamadan University of Medical Sciences, which is published quarterly. Since 2017, JRHS is published electronically. JRHS is a peer-reviewed, scientific publication which is produced quarterly and is a multidisciplinary journal in the field of public health, publishing contributions from Epidemiology, Biostatistics, Public Health, Occupational Health, Environmental Health, Health Education, and Preventive and Social Medicine. We do not publish clinical trials, nursing studies, animal studies, qualitative studies, nutritional studies, health insurance, and hospital management. In addition, we do not publish the results of laboratory and chemical studies in the field of ergonomics, occupational health, and environmental health
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