Song Wu, Huiru Wang, Yuwei Zhao, Bo Tang, Qi Zhang, Dapeng Li
{"title":"黄体酮序贯治疗对围绝经期功能失调性子宫出血促卵泡激素(FSH)、黄体生成素(LH)和雌二醇(E2)的影响。","authors":"Song Wu, Huiru Wang, Yuwei Zhao, Bo Tang, Qi Zhang, Dapeng Li","doi":"10.5937/jomb0-53229","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Perimenopausal dysfunctional uterine bleeding (PDUB) is a common gynaecological disease with various clinical treatment options. The objective of this work was to investigate the clinical effect of female progesterone sequential therapy (FPST) on PDUB and follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2).</p><p><strong>Methods: </strong>140 cases of PDUB patients were enrolled and randomly rolled into an observation (Obs) group and a control (Ctrl) group, with 70 cases in each. The patients in the Ctrl group were given pure curettage treatment, and those in the Obs group were supplemented with FPST based on the intervention in the Ctrl group.</p>","PeriodicalId":16175,"journal":{"name":"Journal of Medical Biochemistry","volume":"44 3","pages":"653-659"},"PeriodicalIF":1.5000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357627/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of progesterone sequential therapy on follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) in perimenopausal dysfunctional uterine bleeding.\",\"authors\":\"Song Wu, Huiru Wang, Yuwei Zhao, Bo Tang, Qi Zhang, Dapeng Li\",\"doi\":\"10.5937/jomb0-53229\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Perimenopausal dysfunctional uterine bleeding (PDUB) is a common gynaecological disease with various clinical treatment options. The objective of this work was to investigate the clinical effect of female progesterone sequential therapy (FPST) on PDUB and follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2).</p><p><strong>Methods: </strong>140 cases of PDUB patients were enrolled and randomly rolled into an observation (Obs) group and a control (Ctrl) group, with 70 cases in each. The patients in the Ctrl group were given pure curettage treatment, and those in the Obs group were supplemented with FPST based on the intervention in the Ctrl group.</p>\",\"PeriodicalId\":16175,\"journal\":{\"name\":\"Journal of Medical Biochemistry\",\"volume\":\"44 3\",\"pages\":\"653-659\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357627/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Biochemistry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5937/jomb0-53229\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Biochemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5937/jomb0-53229","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Effect of progesterone sequential therapy on follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) in perimenopausal dysfunctional uterine bleeding.
Background: Perimenopausal dysfunctional uterine bleeding (PDUB) is a common gynaecological disease with various clinical treatment options. The objective of this work was to investigate the clinical effect of female progesterone sequential therapy (FPST) on PDUB and follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2).
Methods: 140 cases of PDUB patients were enrolled and randomly rolled into an observation (Obs) group and a control (Ctrl) group, with 70 cases in each. The patients in the Ctrl group were given pure curettage treatment, and those in the Obs group were supplemented with FPST based on the intervention in the Ctrl group.
期刊介绍:
The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly.
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clinical hematology and coagulation,
clinical immunology and autoimmunity,
clinical microbiology,
virology,
clinical genomics and molecular biology,
genetic epidemiology,
drug measurement,
evaluation of diagnostic markers,
new reagents and laboratory equipment,
reference materials and methods,
reference values,
laboratory organization,
automation,
quality control,
clinical metrology,
all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.