Dawei Sun, Zhiqiang Li, Daxu Li, Baolei Wu, Yiwei Ma
{"title":"YAG激光联合机械清创治疗牙周炎伴种植周炎,可有效缓解疼痛和控制炎症。","authors":"Dawei Sun, Zhiqiang Li, Daxu Li, Baolei Wu, Yiwei Ma","doi":"10.62347/VIOT6629","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of Er: YAG laser combined with mechanical debridement in treating periodontitis with peri-implantitis.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 292 patients treated between 2018 and 2024. The patients were divided into an observation group (n=139, Er: YAG laser + mechanical debridement) and a control group (n=153, mechanical debridement only). Outcome measures included Visual Analog Scale (VAS) scores, periodontal probing depth (PD), clinical attachment level (CAL), bleeding index (BI), gingival index (GI), and TNF-α/IL-6 levels. Clinical efficacy and risk factors for treatment failure were analyzed using logistic regression.</p><p><strong>Results: </strong>The observation group exhibited a significantly higher total efficacy rate than the control group (89.21% vs. 64.71%, P<0.001). Additionally, VAS scores, PD, CAL, BI, GI, and TNF-α/IL-6 levels were significantly lower at 1 week, 2 weeks, and 1 month post-treatment in the observation group (all P<0.05). Multivariate logistic regression identified age (OR=1.12, 95% CI: 1.07-1.18, P<0.001), smoking (OR=6.21, 95% CI: 2.96-13.82, P<0.001), and diabetes (OR=5.74, 95% CI: 2.71-12.94, P<0.001) as independent risk factors for treatment failure, while postprandial gargling (OR=0.28, P=0.002) was identified as a protective factor.</p><p><strong>Conclusion: </strong>Er: YAG laser combined with mechanical debridement significantly reduced pain and inflammation, improving peri-implant health. Smoking, diabetes, and age increased treatment failure risk, while postprandial gargling was protective, underscoring the importance of personalized treatment strategies.</p>","PeriodicalId":7731,"journal":{"name":"American journal of translational research","volume":"17 7","pages":"5698-5709"},"PeriodicalIF":1.6000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351621/pdf/","citationCount":"0","resultStr":"{\"title\":\"YAG laser combined with mechanical debridement enhances pain relief and inflammation control in the management of periodontitis with peri-implantitis.\",\"authors\":\"Dawei Sun, Zhiqiang Li, Daxu Li, Baolei Wu, Yiwei Ma\",\"doi\":\"10.62347/VIOT6629\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the efficacy of Er: YAG laser combined with mechanical debridement in treating periodontitis with peri-implantitis.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 292 patients treated between 2018 and 2024. The patients were divided into an observation group (n=139, Er: YAG laser + mechanical debridement) and a control group (n=153, mechanical debridement only). Outcome measures included Visual Analog Scale (VAS) scores, periodontal probing depth (PD), clinical attachment level (CAL), bleeding index (BI), gingival index (GI), and TNF-α/IL-6 levels. Clinical efficacy and risk factors for treatment failure were analyzed using logistic regression.</p><p><strong>Results: </strong>The observation group exhibited a significantly higher total efficacy rate than the control group (89.21% vs. 64.71%, P<0.001). Additionally, VAS scores, PD, CAL, BI, GI, and TNF-α/IL-6 levels were significantly lower at 1 week, 2 weeks, and 1 month post-treatment in the observation group (all P<0.05). Multivariate logistic regression identified age (OR=1.12, 95% CI: 1.07-1.18, P<0.001), smoking (OR=6.21, 95% CI: 2.96-13.82, P<0.001), and diabetes (OR=5.74, 95% CI: 2.71-12.94, P<0.001) as independent risk factors for treatment failure, while postprandial gargling (OR=0.28, P=0.002) was identified as a protective factor.</p><p><strong>Conclusion: </strong>Er: YAG laser combined with mechanical debridement significantly reduced pain and inflammation, improving peri-implant health. Smoking, diabetes, and age increased treatment failure risk, while postprandial gargling was protective, underscoring the importance of personalized treatment strategies.</p>\",\"PeriodicalId\":7731,\"journal\":{\"name\":\"American journal of translational research\",\"volume\":\"17 7\",\"pages\":\"5698-5709\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351621/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of translational research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.62347/VIOT6629\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of translational research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.62347/VIOT6629","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
摘要
目的:评价Er: YAG激光联合机械清创治疗牙周炎伴种植周炎的疗效。方法:回顾性分析2018 - 2024年收治的292例患者。将患者分为观察组(n=139, Er: YAG激光+机械清创)和对照组(n=153,单纯机械清创)。结果测量包括视觉模拟量表(VAS)评分、牙周探查深度(PD)、临床附着水平(CAL)、出血指数(BI)、牙龈指数(GI)和TNF-α/IL-6水平。采用logistic回归分析临床疗效及治疗失败的危险因素。结果:观察组总有效率明显高于对照组(89.21% vs. 64.71%)。结论:Er: YAG激光联合机械清创可明显减轻患者疼痛和炎症,改善种植周健康状况。吸烟、糖尿病和年龄增加了治疗失败的风险,而餐后漱口具有保护作用,强调了个性化治疗策略的重要性。
YAG laser combined with mechanical debridement enhances pain relief and inflammation control in the management of periodontitis with peri-implantitis.
Objective: To evaluate the efficacy of Er: YAG laser combined with mechanical debridement in treating periodontitis with peri-implantitis.
Methods: A retrospective analysis was conducted on 292 patients treated between 2018 and 2024. The patients were divided into an observation group (n=139, Er: YAG laser + mechanical debridement) and a control group (n=153, mechanical debridement only). Outcome measures included Visual Analog Scale (VAS) scores, periodontal probing depth (PD), clinical attachment level (CAL), bleeding index (BI), gingival index (GI), and TNF-α/IL-6 levels. Clinical efficacy and risk factors for treatment failure were analyzed using logistic regression.
Results: The observation group exhibited a significantly higher total efficacy rate than the control group (89.21% vs. 64.71%, P<0.001). Additionally, VAS scores, PD, CAL, BI, GI, and TNF-α/IL-6 levels were significantly lower at 1 week, 2 weeks, and 1 month post-treatment in the observation group (all P<0.05). Multivariate logistic regression identified age (OR=1.12, 95% CI: 1.07-1.18, P<0.001), smoking (OR=6.21, 95% CI: 2.96-13.82, P<0.001), and diabetes (OR=5.74, 95% CI: 2.71-12.94, P<0.001) as independent risk factors for treatment failure, while postprandial gargling (OR=0.28, P=0.002) was identified as a protective factor.
Conclusion: Er: YAG laser combined with mechanical debridement significantly reduced pain and inflammation, improving peri-implant health. Smoking, diabetes, and age increased treatment failure risk, while postprandial gargling was protective, underscoring the importance of personalized treatment strategies.