{"title":"大肠黏膜下靶向递送益生菌和大黄酸治疗溃疡性结肠炎的研究（Sci. 30/2025）","authors":"Lingqiang Li, Linxin Dai, Meisi Lin, Shuang He, Hongye Du, Dasheng Lin, Yanbin Wang, Fenglian Zhang, Sian Tao, Xiaoluo Sun, Xinggui Huang, Haihui Liu, Qian Wang, Lingling He, Kunhe Wu, Jieshu You, Minyue Zhang, Chaomei Fu, He Tu, Naijing Ye, Jibin Liu, Fei Gao","doi":"10.1002/advs.71160","DOIUrl":null,"url":null,"abstract":"<p><b>Submucosal Delivery for Intestinal Barrier Repair</b></p><p>The image emphasizes a novel delivery drug channel was dredged, based on a micro-carrier. This system delivers probiotics and drugs precisely to the colonic patches (CPs) via microfolds cells, which initiate a rescue operation of intestinal barrier from colonic submucosa. Confidently, this presents an advanced strategy for treating and preventing colitis, potentially providing more valuable insights into applying submucosal delivery and CPs for additional diseases. Further information is extended in article 2409711 by Naijing Ye, Jibin Liu, Fei Gao, and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"12 30","pages":""},"PeriodicalIF":14.1000,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/advs.71160","citationCount":"0","resultStr":"{\"title\":\"Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment (Adv. Sci. 30/2025)\",\"authors\":\"Lingqiang Li, Linxin Dai, Meisi Lin, Shuang He, Hongye Du, Dasheng Lin, Yanbin Wang, Fenglian Zhang, Sian Tao, Xiaoluo Sun, Xinggui Huang, Haihui Liu, Qian Wang, Lingling He, Kunhe Wu, Jieshu You, Minyue Zhang, Chaomei Fu, He Tu, Naijing Ye, Jibin Liu, Fei Gao\",\"doi\":\"10.1002/advs.71160\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Submucosal Delivery for Intestinal Barrier Repair</b></p><p>The image emphasizes a novel delivery drug channel was dredged, based on a micro-carrier. This system delivers probiotics and drugs precisely to the colonic patches (CPs) via microfolds cells, which initiate a rescue operation of intestinal barrier from colonic submucosa. Confidently, this presents an advanced strategy for treating and preventing colitis, potentially providing more valuable insights into applying submucosal delivery and CPs for additional diseases. Further information is extended in article 2409711 by Naijing Ye, Jibin Liu, Fei Gao, and co-workers.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":117,\"journal\":{\"name\":\"Advanced Science\",\"volume\":\"12 30\",\"pages\":\"\"},\"PeriodicalIF\":14.1000,\"publicationDate\":\"2025-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/advs.71160\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Science\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.71160\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Science","FirstCategoryId":"88","ListUrlMain":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.71160","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment (Adv. Sci. 30/2025)
Submucosal Delivery for Intestinal Barrier Repair
The image emphasizes a novel delivery drug channel was dredged, based on a micro-carrier. This system delivers probiotics and drugs precisely to the colonic patches (CPs) via microfolds cells, which initiate a rescue operation of intestinal barrier from colonic submucosa. Confidently, this presents an advanced strategy for treating and preventing colitis, potentially providing more valuable insights into applying submucosal delivery and CPs for additional diseases. Further information is extended in article 2409711 by Naijing Ye, Jibin Liu, Fei Gao, and co-workers.
期刊介绍：
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.
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