细胞膜脂质重组蛋白生物传感器

IF 1.4 Q4 CELL BIOLOGY

Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology Pub Date : 2025-08-18 DOI:10.1134/S1990747825700205

E. M. Koltsova, N. A. Kolchin, E. I. Nikolaeva, K. R. Butov

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引用次数: 0

摘要

细胞膜中脂质分布的特定模式决定了它们的结构和信号作用，并确保了质膜和细胞器的完整性和功能。重组脂质生物传感器和成像技术的最新进展使我们能够直接观察细胞内脂质的分布、运动和动态，极大地扩展了对脂质功能及其在细胞和亚细胞过程中的作用的理解。本文就重组蛋白传感器在细胞膜中各种脂类的研究进展及应用作一综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Recombinant Protein Biosensors of Cell Membrane Lipids

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Recombinant Protein Biosensors of Cell Membrane Lipids

Specific patterns of lipid distribution in cell membranes determine their structural and signaling roles and ensure the integrity and functionality of the plasma membrane and cell organelles. Recent advances in the development of recombinant lipid biosensors and imaging techniques allow direct observation of the distribution, movement, and dynamics of lipids within cells, significantly expanding the understanding of lipid functions and their involvement in cellular and subcellular processes. In this review, we summarize the data related to the development and application of recombinant protein sensors for various lipids in cell membranes.

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来源期刊

Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology CELL BIOLOGY-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology is an international peer reviewed journal that publishes original articles on physical, chemical, and molecular mechanisms that underlie basic properties of biological membranes and mediate membrane-related cellular functions. The primary topics of the journal are membrane structure, mechanisms of membrane transport, bioenergetics and photobiology, intracellular signaling as well as membrane aspects of cell biology, immunology, and medicine. The journal is multidisciplinary and gives preference to those articles that employ a variety of experimental approaches, basically in biophysics but also in biochemistry, cytology, and molecular biology. The journal publishes articles that strive for unveiling membrane and cellular functions through innovative theoretical models and computer simulations.