Robert R. Attaran MD, FSCAI , Matthew L. Edwards DO, FSCAI , Frank J. Arena MD, FSCAI , Matthew C. Bunte MD, MS, FSCAI , Jeffrey G. Carr MD, FSCAI , Yulanka Castro-Dominguez MD, FSCAI , Andrey Espinoza MD, FSCAI , Dmitriy N. Feldman MD, FSCAI , Scott Firestone MS , Eri Fukaya MD , Karem Harth MD , Beau M. Hawkins MD, FSCAI , Sasanka N. Jayasuriya MD, FSCAI , Pamela Kim MD , Faisal Latif MD, FSCAI , Sahil A. Parikh MD, FSCAI , Eric A. Secemsky MD, MSc, FSCAI , Emily Senerth MS, MPH , Yngve Falck-Ytter MD , Rebecca L. Morgan PhD, MPH
{"title":"2025 SCAI慢性静脉疾病管理临床实践指南","authors":"Robert R. Attaran MD, FSCAI , Matthew L. Edwards DO, FSCAI , Frank J. Arena MD, FSCAI , Matthew C. Bunte MD, MS, FSCAI , Jeffrey G. Carr MD, FSCAI , Yulanka Castro-Dominguez MD, FSCAI , Andrey Espinoza MD, FSCAI , Dmitriy N. Feldman MD, FSCAI , Scott Firestone MS , Eri Fukaya MD , Karem Harth MD , Beau M. Hawkins MD, FSCAI , Sasanka N. Jayasuriya MD, FSCAI , Pamela Kim MD , Faisal Latif MD, FSCAI , Sahil A. Parikh MD, FSCAI , Eric A. Secemsky MD, MSc, FSCAI , Emily Senerth MS, MPH , Yngve Falck-Ytter MD , Rebecca L. Morgan PhD, MPH","doi":"10.1016/j.jscai.2025.103729","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Chronic venous disease (CVD) is a common vascular condition that can have debilitating effects on quality of life and daily function. The Society for Cardiovascular Angiography & Interventions (SCAI) sought to develop evidence-based guidelines to support patients, clinicians, and other stakeholders in their treatment decisions about management of CVD.</div></div><div><h3>Methods</h3><div>SCAI convened a balanced multidisciplinary guideline panel to minimize potential bias from conflicts of interest. The Evidence Foundation, a registered 501(c)(3) nonprofit organization, provided methodological support for the development of the guidelines. The guideline panel formulated and prioritized clinical questions following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach in population, intervention, comparison, outcome format. A technical review team of clinical and methodological experts conducted systematic reviews of the published evidence, synthesized data, and graded the certainty of the evidence across outcomes. The guideline panel then reconvened to develop recommendations and supporting remarks informed by the results of the technical review, as well as additional contextual factors described in the GRADE evidence-to-decision framework.</div></div><div><h3>Results</h3><div>The guideline panel reached consensus on 9 recommendations to address variations in treatment of CVD across 8 different clinical scenarios. The panel also identified 4 anatomical scenarios with significant knowledge gaps.</div></div><div><h3>Conclusions</h3><div>Key recommendations address patient selection for compression therapy, ablation of saphenous and perforator veins, sclerotherapy, phlebectomy, and deep vein revascularization. Two algorithms for the management of symptomatic varicose veins and venous ulcer disease were created to facilitate implementation of these evidence-based recommendations. The panel also identified several anatomical and clinical areas where future research is needed to advance the CVD field.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 8","pages":"Article 103729"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"2025 SCAI Clinical Practice Guidelines for the Management of Chronic Venous Disease\",\"authors\":\"Robert R. Attaran MD, FSCAI , Matthew L. Edwards DO, FSCAI , Frank J. Arena MD, FSCAI , Matthew C. Bunte MD, MS, FSCAI , Jeffrey G. Carr MD, FSCAI , Yulanka Castro-Dominguez MD, FSCAI , Andrey Espinoza MD, FSCAI , Dmitriy N. Feldman MD, FSCAI , Scott Firestone MS , Eri Fukaya MD , Karem Harth MD , Beau M. Hawkins MD, FSCAI , Sasanka N. Jayasuriya MD, FSCAI , Pamela Kim MD , Faisal Latif MD, FSCAI , Sahil A. Parikh MD, FSCAI , Eric A. Secemsky MD, MSc, FSCAI , Emily Senerth MS, MPH , Yngve Falck-Ytter MD , Rebecca L. Morgan PhD, MPH\",\"doi\":\"10.1016/j.jscai.2025.103729\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Chronic venous disease (CVD) is a common vascular condition that can have debilitating effects on quality of life and daily function. The Society for Cardiovascular Angiography & Interventions (SCAI) sought to develop evidence-based guidelines to support patients, clinicians, and other stakeholders in their treatment decisions about management of CVD.</div></div><div><h3>Methods</h3><div>SCAI convened a balanced multidisciplinary guideline panel to minimize potential bias from conflicts of interest. The Evidence Foundation, a registered 501(c)(3) nonprofit organization, provided methodological support for the development of the guidelines. The guideline panel formulated and prioritized clinical questions following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach in population, intervention, comparison, outcome format. A technical review team of clinical and methodological experts conducted systematic reviews of the published evidence, synthesized data, and graded the certainty of the evidence across outcomes. The guideline panel then reconvened to develop recommendations and supporting remarks informed by the results of the technical review, as well as additional contextual factors described in the GRADE evidence-to-decision framework.</div></div><div><h3>Results</h3><div>The guideline panel reached consensus on 9 recommendations to address variations in treatment of CVD across 8 different clinical scenarios. The panel also identified 4 anatomical scenarios with significant knowledge gaps.</div></div><div><h3>Conclusions</h3><div>Key recommendations address patient selection for compression therapy, ablation of saphenous and perforator veins, sclerotherapy, phlebectomy, and deep vein revascularization. Two algorithms for the management of symptomatic varicose veins and venous ulcer disease were created to facilitate implementation of these evidence-based recommendations. The panel also identified several anatomical and clinical areas where future research is needed to advance the CVD field.</div></div>\",\"PeriodicalId\":73990,\"journal\":{\"name\":\"Journal of the Society for Cardiovascular Angiography & Interventions\",\"volume\":\"4 8\",\"pages\":\"Article 103729\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Society for Cardiovascular Angiography & Interventions\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772930325011718\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Society for Cardiovascular Angiography & Interventions","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772930325011718","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
2025 SCAI Clinical Practice Guidelines for the Management of Chronic Venous Disease
Background
Chronic venous disease (CVD) is a common vascular condition that can have debilitating effects on quality of life and daily function. The Society for Cardiovascular Angiography & Interventions (SCAI) sought to develop evidence-based guidelines to support patients, clinicians, and other stakeholders in their treatment decisions about management of CVD.
Methods
SCAI convened a balanced multidisciplinary guideline panel to minimize potential bias from conflicts of interest. The Evidence Foundation, a registered 501(c)(3) nonprofit organization, provided methodological support for the development of the guidelines. The guideline panel formulated and prioritized clinical questions following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach in population, intervention, comparison, outcome format. A technical review team of clinical and methodological experts conducted systematic reviews of the published evidence, synthesized data, and graded the certainty of the evidence across outcomes. The guideline panel then reconvened to develop recommendations and supporting remarks informed by the results of the technical review, as well as additional contextual factors described in the GRADE evidence-to-decision framework.
Results
The guideline panel reached consensus on 9 recommendations to address variations in treatment of CVD across 8 different clinical scenarios. The panel also identified 4 anatomical scenarios with significant knowledge gaps.
Conclusions
Key recommendations address patient selection for compression therapy, ablation of saphenous and perforator veins, sclerotherapy, phlebectomy, and deep vein revascularization. Two algorithms for the management of symptomatic varicose veins and venous ulcer disease were created to facilitate implementation of these evidence-based recommendations. The panel also identified several anatomical and clinical areas where future research is needed to advance the CVD field.