纳米结构氧化铯的抗菌活性研究

IF 4.1 3区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY
Wedam Alghazzawi
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引用次数: 0

摘要

随着细菌菌株对抗生素的耐药性越来越强,许多研究人员正在寻找新的、有效的、廉价的抗生素。一些纳米材料被认为是新型抗菌剂的潜在候选材料。本研究合成了氧化铯纳米颗粒,并对其抑制细菌生长的能力进行了初步研究。虽然关于氧化铯的应用研究很少,但这种氧化物可能对生物活性产生重大影响。在500℃下快速煅烧3 h合成氧化铯纳米颗粒,通过x射线衍射、傅里叶变换红外光谱、能量色散x射线光谱和扫描电镜分析对制备样品的组成和形貌进行表征,验证了氧化铯纳米颗粒的合成。采用琼脂孔扩散法和最低抑菌浓度法研究了氧化铯纳米颗粒对革兰氏阳性菌和革兰氏阴性菌的抑菌活性。实验结果为开发氧化铯纳米结构作为抗多种细菌感染和疾病的抗菌剂提供了初步支持。图形抽象
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibacterial activity of promising nanostructured cesium oxide

As bacterial strains become increasingly resistant to antibiotics, many researchers are seeking novel, effective, and inexpensive antibiotics. Some nanomaterials have been suggested as potential candidates for use as novel antibacterial agents. In this study, cesium oxide nanoparticles were synthesized and preliminarily investigated for their ability to inhibit the growth of bacteria. Although there are few studies on the applications of cesium oxide, it is possible that this oxide could have a substantial impact on biological activities. Cesium oxide nanoparticles were synthesized via fast calcination at 500 °C for 3 h. The composition and morphology of the prepared samples were characterized via X-ray diffraction, Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, and scanning electron microscope analysis, which verified the synthesis of cesium oxide nanoparticles. Agar well diffusion and minimum inhibitory concentration assays were used to study the antibacterial activity of cesium oxide nanoparticles against gram-positive and gram-negative bacteria. The experimental results provide preliminary support for developing cesium oxide nanostructures as antibacterial agents against a wide range of infections and diseases caused by bacteria.

Graphical abstract

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来源期刊
Nanoscale Research Letters
Nanoscale Research Letters 工程技术-材料科学:综合
CiteScore
11.30
自引率
0.00%
发文量
110
审稿时长
48 days
期刊介绍: Nanoscale Research Letters (NRL) provides an interdisciplinary forum for communication of scientific and technological advances in the creation and use of objects at the nanometer scale. NRL is the first nanotechnology journal from a major publisher to be published with Open Access.
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