Shafie Abdulkadir Hassan , Mowlid Abdikarin Mohamed , Zeynab Abdi Salad , Nimo Dahir Mohamed , Fardowsa Abdulahi Ahmed , Farhan Abdiaziz Dirie , Mohamed Khalif Abdulle , Abdifetah Ibrahim Omar , Nur Rashid Ahmed
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Data analysis was conducted using SPSS software, with results presented as frequencies and percentages. Chi-square tests and binary logistic regression were performed to identify associations between MRSA and independent variables.</div></div><div><h3>Results</h3><div><em>S. aureus</em> was isolated in 116 (27.8%) patients, with 31 (26.7%) cases identified as MRSA. The prevalence of MRSA was higher among females (10, 27%) than males (21, 26.6%). The most frequent MRSA was observed in the 21-30 years age group (13, 24.5%). Patients with deep wounds had a significant association with MRSA (adjusted odds ratio [AOR]: 4.32, 95% confidence interval [CI]: 1.042-17.92, <em>P</em> <0.044). Hospital stay of longer than 72 hours (AOR: 4.1, 95% CI: 1.22-13.80, <em>P</em> <0.022) and history of antibiotic use (AOR: 1.12, 95% CI: 0.17-7.15, <em>P</em> <0.018) were also found significant risk factors. Penicillin was 100% resistant to MRSA, followed by 58% to cotrimoxazole, 54.8% to gentamycin, and 51.6% to ciprofloxacin, whereas MRSA was 100% susceptible to vancomycin.</div></div><div><h3>Conclusions</h3><div>The prevalence of MRSA among inpatients with surgical wounds is considerable, with specific risk factors such as deep wounds, prolonged hospital stays, and previous antibiotic use significantly increasing the likelihood of MRSA infection. Antibiogram results indicated a significant resistance to frequently used antibiotics. This emphasizes the importance of implementing effective infection control measures and practicing antibiotic stewardship to manage MRSA in hospitals.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"16 ","pages":"Article 100717"},"PeriodicalIF":1.7000,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of methicillin-resistant Staphylococcus aureus and associated factors from surgical ward inpatients at Shaafi Hospital, Mogadishu, Somalia\",\"authors\":\"Shafie Abdulkadir Hassan , Mowlid Abdikarin Mohamed , Zeynab Abdi Salad , Nimo Dahir Mohamed , Fardowsa Abdulahi Ahmed , Farhan Abdiaziz Dirie , Mohamed Khalif Abdulle , Abdifetah Ibrahim Omar , Nur Rashid Ahmed\",\"doi\":\"10.1016/j.ijregi.2025.100717\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) causes severe infections with high mortality rates and health care costs. This study aimed to evaluate the prevalence of MRSA and its associated factors among patients with wound infections at Shaafi Hospital in Mogadishu, Somalia.</div></div><div><h3>Methods</h3><div>Wound swabs were collected from 418 patients with surgical wounds and cultured on Mannitol salt agar. <em>S. aureus</em> was identified using conventional methods, and antimicrobial susceptibility was performed using the disk diffusion method. Data analysis was conducted using SPSS software, with results presented as frequencies and percentages. Chi-square tests and binary logistic regression were performed to identify associations between MRSA and independent variables.</div></div><div><h3>Results</h3><div><em>S. aureus</em> was isolated in 116 (27.8%) patients, with 31 (26.7%) cases identified as MRSA. The prevalence of MRSA was higher among females (10, 27%) than males (21, 26.6%). The most frequent MRSA was observed in the 21-30 years age group (13, 24.5%). Patients with deep wounds had a significant association with MRSA (adjusted odds ratio [AOR]: 4.32, 95% confidence interval [CI]: 1.042-17.92, <em>P</em> <0.044). Hospital stay of longer than 72 hours (AOR: 4.1, 95% CI: 1.22-13.80, <em>P</em> <0.022) and history of antibiotic use (AOR: 1.12, 95% CI: 0.17-7.15, <em>P</em> <0.018) were also found significant risk factors. Penicillin was 100% resistant to MRSA, followed by 58% to cotrimoxazole, 54.8% to gentamycin, and 51.6% to ciprofloxacin, whereas MRSA was 100% susceptible to vancomycin.</div></div><div><h3>Conclusions</h3><div>The prevalence of MRSA among inpatients with surgical wounds is considerable, with specific risk factors such as deep wounds, prolonged hospital stays, and previous antibiotic use significantly increasing the likelihood of MRSA infection. Antibiogram results indicated a significant resistance to frequently used antibiotics. 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引用次数: 0
摘要
目的耐甲氧西林金黄色葡萄球菌（MRSA）感染严重，死亡率高，医疗费用高。本研究旨在评估索马里摩加迪沙Shaafi医院伤口感染患者中MRSA的患病率及其相关因素。方法收集418例外科创面伤口拭子，用甘露醇盐琼脂培养。采用常规方法鉴定金黄色葡萄球菌，采用纸片扩散法进行药敏试验。数据分析采用SPSS软件，结果以频率和百分比表示。采用卡方检验和二元logistic回归分析MRSA与自变量之间的关系。116例（27.8%）患者分离到金黄色葡萄球菌，其中31例（26.7%）被鉴定为MRSA。MRSA在女性中的患病率（10.27%）高于男性（21.26.6%）。MRSA最常见于21 ~ 30岁年龄组（13.24.5%）。深伤口患者与MRSA有显著相关性（调整优势比[AOR]: 4.32, 95%可信区间[CI]: 1.042-17.92, P <0.044）。住院时间超过72小时（AOR: 4.1, 95% CI: 1.22-13.80, P <0.022）和抗生素使用史（AOR: 1.12, 95% CI: 0.17-7.15, P <0.018）也是显著的危险因素。青霉素对MRSA的耐药率为100%，其次是复方新诺明为58%，庆大霉素为54.8%，环丙沙星为51.6%，而MRSA对万古霉素的耐药率为100%。结论MRSA在外科伤口住院患者中的患病率相当高，伤口较深、住院时间较长、既往使用抗生素等特定危险因素显著增加了MRSA感染的可能性。抗生素造影结果显示对常用抗生素有明显耐药性。这强调了实施有效的感染控制措施和实施抗生素管理的重要性，以管理MRSA在医院。
Prevalence of methicillin-resistant Staphylococcus aureus and associated factors from surgical ward inpatients at Shaafi Hospital, Mogadishu, Somalia
Objectives
Methicillin-resistant Staphylococcus aureus (MRSA) causes severe infections with high mortality rates and health care costs. This study aimed to evaluate the prevalence of MRSA and its associated factors among patients with wound infections at Shaafi Hospital in Mogadishu, Somalia.
Methods
Wound swabs were collected from 418 patients with surgical wounds and cultured on Mannitol salt agar. S. aureus was identified using conventional methods, and antimicrobial susceptibility was performed using the disk diffusion method. Data analysis was conducted using SPSS software, with results presented as frequencies and percentages. Chi-square tests and binary logistic regression were performed to identify associations between MRSA and independent variables.
Results
S. aureus was isolated in 116 (27.8%) patients, with 31 (26.7%) cases identified as MRSA. The prevalence of MRSA was higher among females (10, 27%) than males (21, 26.6%). The most frequent MRSA was observed in the 21-30 years age group (13, 24.5%). Patients with deep wounds had a significant association with MRSA (adjusted odds ratio [AOR]: 4.32, 95% confidence interval [CI]: 1.042-17.92, P <0.044). Hospital stay of longer than 72 hours (AOR: 4.1, 95% CI: 1.22-13.80, P <0.022) and history of antibiotic use (AOR: 1.12, 95% CI: 0.17-7.15, P <0.018) were also found significant risk factors. Penicillin was 100% resistant to MRSA, followed by 58% to cotrimoxazole, 54.8% to gentamycin, and 51.6% to ciprofloxacin, whereas MRSA was 100% susceptible to vancomycin.
Conclusions
The prevalence of MRSA among inpatients with surgical wounds is considerable, with specific risk factors such as deep wounds, prolonged hospital stays, and previous antibiotic use significantly increasing the likelihood of MRSA infection. Antibiogram results indicated a significant resistance to frequently used antibiotics. This emphasizes the importance of implementing effective infection control measures and practicing antibiotic stewardship to manage MRSA in hospitals.
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