{"title":"一名新诊断为Wilson病的青少年伴有潜在的1型糖尿病:一种以前未报道的组合。","authors":"Neeraj Kumar, Sunisha Jakhar, Dinkar Yadav, Neha Yadav, Kapil Bhalla","doi":"10.4103/jfmpc.jfmpc_1820_24","DOIUrl":null,"url":null,"abstract":"<p><p>Wilson's disease is a copper deposition disease; involving the brain, liver, and eyes with onset commonly in adolescent age group. The onset of symptoms typically occurs around 12-15 years of age. The usual manifestations are hepatic (40% of the cases), neurological (35%) or psychiatric (10%). It has been seen associated with various endocrinopathies like hypothyroidism and hypoparathyroidism but its association with type 1 diabetes mellitus very rare. To the best of our knowledge, no case has been reported about association of type 1 diabetes mellitus with Wilson disease. Here we report a case of 14-year-old male patient, who was diagnosed with type 1 diabetes mellitus one year back, now presented with neurological symptoms. On further investigations patient was found to have Wilson's disease.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"14 7","pages":"3019-3021"},"PeriodicalIF":1.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12349813/pdf/","citationCount":"0","resultStr":"{\"title\":\"An adolescent with newly diagnosed Wilson disease having underlying type 1 diabetes: A previously unreported combination.\",\"authors\":\"Neeraj Kumar, Sunisha Jakhar, Dinkar Yadav, Neha Yadav, Kapil Bhalla\",\"doi\":\"10.4103/jfmpc.jfmpc_1820_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Wilson's disease is a copper deposition disease; involving the brain, liver, and eyes with onset commonly in adolescent age group. The onset of symptoms typically occurs around 12-15 years of age. The usual manifestations are hepatic (40% of the cases), neurological (35%) or psychiatric (10%). It has been seen associated with various endocrinopathies like hypothyroidism and hypoparathyroidism but its association with type 1 diabetes mellitus very rare. To the best of our knowledge, no case has been reported about association of type 1 diabetes mellitus with Wilson disease. Here we report a case of 14-year-old male patient, who was diagnosed with type 1 diabetes mellitus one year back, now presented with neurological symptoms. On further investigations patient was found to have Wilson's disease.</p>\",\"PeriodicalId\":15856,\"journal\":{\"name\":\"Journal of Family Medicine and Primary Care\",\"volume\":\"14 7\",\"pages\":\"3019-3021\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12349813/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Family Medicine and Primary Care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jfmpc.jfmpc_1820_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/21 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"PRIMARY HEALTH CARE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Family Medicine and Primary Care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jfmpc.jfmpc_1820_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/21 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PRIMARY HEALTH CARE","Score":null,"Total":0}
An adolescent with newly diagnosed Wilson disease having underlying type 1 diabetes: A previously unreported combination.
Wilson's disease is a copper deposition disease; involving the brain, liver, and eyes with onset commonly in adolescent age group. The onset of symptoms typically occurs around 12-15 years of age. The usual manifestations are hepatic (40% of the cases), neurological (35%) or psychiatric (10%). It has been seen associated with various endocrinopathies like hypothyroidism and hypoparathyroidism but its association with type 1 diabetes mellitus very rare. To the best of our knowledge, no case has been reported about association of type 1 diabetes mellitus with Wilson disease. Here we report a case of 14-year-old male patient, who was diagnosed with type 1 diabetes mellitus one year back, now presented with neurological symptoms. On further investigations patient was found to have Wilson's disease.