动物发育过程中分泌的卷曲相关蛋白。

IF 2.1 4区生物学 Q4 CELL BIOLOGY

Histochemistry and Cell Biology Pub Date : 2025-08-15 DOI:10.1007/s00418-025-02415-z

Konstantin Sadriev

{"title":"动物发育过程中分泌的卷曲相关蛋白。","authors":"Konstantin Sadriev","doi":"10.1007/s00418-025-02415-z","DOIUrl":null,"url":null,"abstract":"Secreted Frizzled-related proteins (SFRPs) are a small, ancient family of extracellular signaling pathway agonists and antagonists. As part of the intercellular communication system, they regulate signaling pathways significant for animal development including Wnt and BMP. This review summarizes the current knowledge of SFRP functions, focusing on recent discoveries that offer new insights into the role of interactions between SFRPs and Wnt signaling pathways in morphogenesis.","PeriodicalId":13107,"journal":{"name":"Histochemistry and Cell Biology","volume":"163 1","pages":"80"},"PeriodicalIF":2.1000,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Secreted Frizzled-related proteins in animal development.\",\"authors\":\"Konstantin Sadriev\",\"doi\":\"10.1007/s00418-025-02415-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Secreted Frizzled-related proteins (SFRPs) are a small, ancient family of extracellular signaling pathway agonists and antagonists. As part of the intercellular communication system, they regulate signaling pathways significant for animal development including Wnt and BMP. This review summarizes the current knowledge of SFRP functions, focusing on recent discoveries that offer new insights into the role of interactions between SFRPs and Wnt signaling pathways in morphogenesis.\",\"PeriodicalId\":13107,\"journal\":{\"name\":\"Histochemistry and Cell Biology\",\"volume\":\"163 1\",\"pages\":\"80\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Histochemistry and Cell Biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1007/s00418-025-02415-z\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Histochemistry and Cell Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1007/s00418-025-02415-z","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CELL BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

分泌卷曲相关蛋白（SFRPs）是一个小的，古老的细胞外信号通路激动剂和拮抗剂家族。作为细胞间通讯系统的一部分，它们调节包括Wnt和BMP在内的动物发育的重要信号通路。这篇综述总结了目前关于SFRP功能的知识，重点介绍了最近的发现，这些发现为SFRP和Wnt信号通路在形态发生中的相互作用提供了新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Secreted Frizzled-related proteins in animal development.

Secreted Frizzled-related proteins (SFRPs) are a small, ancient family of extracellular signaling pathway agonists and antagonists. As part of the intercellular communication system, they regulate signaling pathways significant for animal development including Wnt and BMP. This review summarizes the current knowledge of SFRP functions, focusing on recent discoveries that offer new insights into the role of interactions between SFRPs and Wnt signaling pathways in morphogenesis.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Histochemistry and Cell Biology 生物-细胞生物学

CiteScore

4.90

自引率

8.70%

发文量

112

审稿时长

1 months

期刊介绍： Histochemistry and Cell Biology is devoted to the field of molecular histology and cell biology, publishing original articles dealing with the localization and identification of molecular components, metabolic activities and cell biological aspects of cells and tissues. Coverage extends to the development, application, and/or evaluation of methods and probes that can be used in the entire area of histochemistry and cell biology.