秀丽隐杆线虫毒理学模型的研究现状及其在法医学中的应用。

Q3 Medicine
Zhuo Li, Yi-Ru Zeng, Zhi-Long Shu, Xue-Hong Sun, Kui Zhang
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引用次数: 0

摘要

秀丽隐杆线虫作为一种新兴的模式生物,由于其生命周期短、遗传背景清晰、进化高度保守、基因组分析完整、实验数据与人体结果拟合良好等特点,近年来被广泛应用于医学、生命科学、环境科学等多个学科。它在毒理学领域也显示出独特的优势。本文从秀丽隐杆线虫的生物学特性出发,总结了其在毒理学研究中的优势,介绍了基于秀丽隐杆线虫模型的毒理学研究方法和进展,重点展示了其在环境法医学和法医毒理学方面的应用,并展望了相关成果在法医学领域的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science.

Caenorhabditis elegans, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background, highly conserved evolution, complete genome analysis and excellent fitting between experimental data and human results. It also shows unique advantages in the field of toxicology. This paper summarizes its advantages in toxicological research starting from the biological characteristics of C. elegans, introduces the toxicological research methods and progress based on the C. elegans model, focuses on demonstrating its applications in environmental forensic medicine and forensic toxicology, and looks forward to the application of the relevant results in the field of forensic science.

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来源期刊
法医学杂志
法医学杂志 Medicine-Pathology and Forensic Medicine
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1.50
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