{"title":"液化气中无金属有机合成：成就与展望","authors":"I. V. Kuchurov, M. N. Zharkov, S. G. Zlotin","doi":"10.1007/s11172-025-4678-3","DOIUrl":null,"url":null,"abstract":"<div><p>The potential of carbon dioxide and 1,1,1,2-tetrafluoroethane in their liquid and supercritical states as environmentally friendly (green) solvents for metal-free liquid-phase chemical transformations has been substantiated. This review summarizes data on <i>N</i>-, <i>O</i>-, and <i>C</i>-nitration carried out in these media. Particular attention is given to the application of liquid (liq-CO<sub>2</sub>) and supercritical carbon dioxide (sc-CO<sub>2</sub>) in condensation of carbonyl compounds with amines, including the one-pot tandem transformations of the resulting imines. The oxidative functionalization of cycloalkanes induced by near-UV light in the presence of nitrogen dioxide under sc-CO<sub>2</sub> conditions is discussed. The effectiveness of sc-CO<sub>2</sub> as a solvent in photooxidation of alcohols and sulfides with molecular oxygen in the presence of such metal-free photocatalysts as 2-fluoroanthraquinone and graphitic carbon nitride is demonstrated. Additionally, recent advances in asymmetric aldol reactions, conjugate additions, and cascade reactions catalyzed by chiral amines in liq-CO<sub>2</sub> and sc-CO<sub>2</sub> media are reviewed.</p></div>","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":"74 7","pages":"1914 - 1928"},"PeriodicalIF":1.7000,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metal-free organic synthesis in liquefied gases: achievements and prospects\",\"authors\":\"I. V. Kuchurov, M. N. Zharkov, S. G. Zlotin\",\"doi\":\"10.1007/s11172-025-4678-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The potential of carbon dioxide and 1,1,1,2-tetrafluoroethane in their liquid and supercritical states as environmentally friendly (green) solvents for metal-free liquid-phase chemical transformations has been substantiated. This review summarizes data on <i>N</i>-, <i>O</i>-, and <i>C</i>-nitration carried out in these media. Particular attention is given to the application of liquid (liq-CO<sub>2</sub>) and supercritical carbon dioxide (sc-CO<sub>2</sub>) in condensation of carbonyl compounds with amines, including the one-pot tandem transformations of the resulting imines. The oxidative functionalization of cycloalkanes induced by near-UV light in the presence of nitrogen dioxide under sc-CO<sub>2</sub> conditions is discussed. The effectiveness of sc-CO<sub>2</sub> as a solvent in photooxidation of alcohols and sulfides with molecular oxygen in the presence of such metal-free photocatalysts as 2-fluoroanthraquinone and graphitic carbon nitride is demonstrated. Additionally, recent advances in asymmetric aldol reactions, conjugate additions, and cascade reactions catalyzed by chiral amines in liq-CO<sub>2</sub> and sc-CO<sub>2</sub> media are reviewed.</p></div>\",\"PeriodicalId\":756,\"journal\":{\"name\":\"Russian Chemical Bulletin\",\"volume\":\"74 7\",\"pages\":\"1914 - 1928\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-08-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Chemical Bulletin\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11172-025-4678-3\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Chemical Bulletin","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11172-025-4678-3","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Metal-free organic synthesis in liquefied gases: achievements and prospects
The potential of carbon dioxide and 1,1,1,2-tetrafluoroethane in their liquid and supercritical states as environmentally friendly (green) solvents for metal-free liquid-phase chemical transformations has been substantiated. This review summarizes data on N-, O-, and C-nitration carried out in these media. Particular attention is given to the application of liquid (liq-CO2) and supercritical carbon dioxide (sc-CO2) in condensation of carbonyl compounds with amines, including the one-pot tandem transformations of the resulting imines. The oxidative functionalization of cycloalkanes induced by near-UV light in the presence of nitrogen dioxide under sc-CO2 conditions is discussed. The effectiveness of sc-CO2 as a solvent in photooxidation of alcohols and sulfides with molecular oxygen in the presence of such metal-free photocatalysts as 2-fluoroanthraquinone and graphitic carbon nitride is demonstrated. Additionally, recent advances in asymmetric aldol reactions, conjugate additions, and cascade reactions catalyzed by chiral amines in liq-CO2 and sc-CO2 media are reviewed.
期刊介绍：
Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections:
General and Inorganic Chemistry;
Physical Chemistry;
Organic Chemistry;
Organometallic Chemistry;
Chemistry of Natural Compounds and Bioorganic Chemistry.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
