一种同步电位/电流非酶多巴胺传感器的传感特性

IF 4.3 2区 综合性期刊 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Jung-Chuan Chou;Wei-Shun Chen;Po-Hui Yang;Yu-Hsun Nien;Chih-Hsien Lai;Po-Yu Kuo;Jyun-Ming Huang;Yu-Wei Chen
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引用次数: 0

摘要

在这项研究中,提出了一种基于化学镍浸金(ENIG)衬底的柔性多巴胺(DA)传感器。Cu2O薄膜具有高导电性和化学稳定性,而WO3纳米颗粒(WO3 NPs)对DA检测具有优异的催化活性和选择性。Cu2O/WO3NPs异质结构可以在电位模式和安培模式下工作,显著提高了其实用性。在0.01-100 - $\mu $ M DA范围内,传感器的平均灵敏度为33.0 mV dec ${}^{-{1}}$(电位计)和$220.7~\mu $ A $\mu $ M ${}^{-{1}}$ cm ${}^{-{2}}$(安培计)。在任何一种操作模式下,检测限、选择性和重现性都在可接受的标准范围内。wo3nps /Cu2O/ENIG传感器对常见干扰具有良好的分辨能力,分析性能一致。这种形式的DA传感器具有巨大的潜力,作为一个多功能的神经递质监测解决方案,在实验室或护理点设置。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sensing Characteristics of a Simultaneous Potentiometric/Amperometric Nonenzymatic Dopamine Sensor
In this study, a flexible dopamine (DA) sensor based on an electroless nickel immersion gold (ENIG) substrate is proposed. A Cu2O thin film provides high electrical conductivity and chemical stability, and WO3 nanoparticles (WO3 NPs) provide excellent catalytic activity and selectivity for DA detection. The Cu2O/WO3NPs heterostructure can be operated in both potentiometric and amperometric modes, markedly increasing its utility. Across 0.01–100- $\mu $ M DA, the sensor delivers average sensitivities of 33.0 mV dec ${}^{-{1}}$ (potentiometric) and $220.7~\mu $ A $\mu $ M ${}^{-{1}}$ cm ${}^{-{2}}$ (amperometric). The detection limits, selectivity, and reproducibility are all within acceptable standards under either mode of operation. The WO3 NPs/Cu2O/ENIG sensor exhibits excellent discrimination against common interferents and has consistent analytical performance. This form of DA sensor has tremendous potential as a versatile neurotransmitter monitoring solution, in either laboratory or point-of-care settings.
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来源期刊
IEEE Sensors Journal
IEEE Sensors Journal 工程技术-工程:电子与电气
CiteScore
7.70
自引率
14.00%
发文量
2058
审稿时长
5.2 months
期刊介绍: The fields of interest of the IEEE Sensors Journal are the theory, design , fabrication, manufacturing and applications of devices for sensing and transducing physical, chemical and biological phenomena, with emphasis on the electronics and physics aspect of sensors and integrated sensors-actuators. IEEE Sensors Journal deals with the following: -Sensor Phenomenology, Modelling, and Evaluation -Sensor Materials, Processing, and Fabrication -Chemical and Gas Sensors -Microfluidics and Biosensors -Optical Sensors -Physical Sensors: Temperature, Mechanical, Magnetic, and others -Acoustic and Ultrasonic Sensors -Sensor Packaging -Sensor Networks -Sensor Applications -Sensor Systems: Signals, Processing, and Interfaces -Actuators and Sensor Power Systems -Sensor Signal Processing for high precision and stability (amplification, filtering, linearization, modulation/demodulation) and under harsh conditions (EMC, radiation, humidity, temperature); energy consumption/harvesting -Sensor Data Processing (soft computing with sensor data, e.g., pattern recognition, machine learning, evolutionary computation; sensor data fusion, processing of wave e.g., electromagnetic and acoustic; and non-wave, e.g., chemical, gravity, particle, thermal, radiative and non-radiative sensor data, detection, estimation and classification based on sensor data) -Sensors in Industrial Practice
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