创新的可生物降解的防腐剂和软膏擦拭先进的伤口管理。

IF 1.5
Arjun Dakuri, P Gopi Chandrakanth, Renuka Tejaswini Lolla, Lalith Kumar, J Hayavadana
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引用次数: 0

摘要

由于对有效、可持续和具有成本效益的解决方案的需求日益增加,特别是在资源匮乏的国家,伤口护理管理已经取得了重大进展。伤口护理的主要目标是加速愈合,减少感染风险,并确保外观和功能恢复。本研究探索了生物基防腐剂和软膏湿巾作为一种环保,负担得起的替代传统伤口敷料的发展。以水刺粘胶织物和竹编织物(72 GSM和114 GSM)的吸水性和生物降解性为研究对象。主要生物活性成分(茶树油、蜂蜡)和婴儿洗发水通过填充法注入。采用标准纺织品和微生物学测试方法评价其对金黄色葡萄球菌和大肠杆菌的物理性能、吸水率(AATCC197)和抗菌效果(aatcc100)。对15名运动员进行主观评价,评估伤口愈合效果。与粘胶织物(10.8 cm)相比,竹材织物表现出优越的排汗高度(120 s时为11.0 cm)。抗菌测试显示,竹样品的金黄色葡萄球菌减少100%,大肠杆菌减少96.2%。运动员试验表明,平均伤口愈合时间为4天,满意度高。成本分析显示,消毒湿巾每单位的成本为0.062美元,软膏湿巾每单位的成本为0.104美元,这使得它们成为合成湿巾的成本效益替代品,并且在经济上可行,可以大规模采用。可生物降解的防腐剂和软膏湿巾注入天然抗菌剂提供可持续和有效的解决方案,伤口护理。其优越的吸收性、抗菌功效和可负担性突出了其在医疗保健领域广泛采用的潜力。未来的研究应侧重于优化配方,以实现更广泛的临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Innovative Biodegradable Antiseptic and Ointment Wipes for Advanced Wound Management.

Wound care management has undergone significant advancements, driven by the increasing need for effective, sustainable, and cost-effective solutions, especially in low-resource countries. The primary goal of wound care is to expedite healing, minimize infection risk, and ensure cosmetic and functional recovery. This study explores the development of biobased antiseptic and ointment wipes as an eco-friendly, affordable alternative to conventional wound dressings. Spunlace viscose and bamboo fabrics (72 GSM and 114 GSM) were selected for their absorbency and biodegradability. Key bioactive components (tea tree oil, beeswax), and baby shampoo were infused via a padding method. Physical properties, water absorbency (AATCC197), and antibacterial effectiveness (AATCC 100) against S. aureus and E. coli were evaluated using standard textile and microbiological test methods. A subjective evaluation with 15 athletes assessed wound healing effectiveness.Bamboo fabric demonstrated superior wicking height (11.0 cm at 120 s) compared to viscose (10.8 cm). Antibacterial testing revealed a 100% reduction in S. aureus and a 96.2% reduction in E. coli for bamboo samples. Athlete trials indicated an average wound healing time of four days with high satisfaction levels. Cost analysis showed antiseptic wipes cost $0.062 per unit, and ointment wipes cost $0.104 per unit, making them cost-effective alternatives to synthetic and economically viable for mass adoption. Biodegradable antiseptic and ointment wipes infused with natural antimicrobial agents offer a sustainable and effective solution for wound care. Their superior absorbency, antibacterial efficacy, and affordability highlight their potential for widespread adoption in healthcare. Future research should focus on optimizing formulations for broader clinical applications.

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