The iron woman: a case report of contemporary cardiac support.

Background: Modern cardiovascular practice utilizes various devices and procedures to treat functional and structural heart disease.

Case summary: We report an interesting case of a female patient with heart failure with reduced ejection fraction (HFrEF) and severe mitral regurgitation who received the full spectrum of available device-based therapies including mitral transcatheter edge-to-edge repair, percutaneous mitral annuloplasty with the Carillon device, temporary mechanical circulatory support, durable left ventricular assist device, and eventually cardiac transplantation.

Discussion: Management of HFrEF and functional mitral regurgitation is a common clinical issue for which numerous devices may be utilized to improve patient symptoms and outcomes. In this report, we review indications, supporting data, and anatomical relationships of some of these devices. We also highlight stepwise progression to advanced heart failure requiring temporary and durable mechanical circulatory support followed ultimately by heart transplantation.