{"title":"光学相干层析成像中使用模式选择光子灯通过相关比精确测量流速。","authors":"Raphaël Maltais-Tariant, Rodrigo Itzamna Becerra-Deana, Simon Brais-Brunet, Mathieu Dehaes, Caroline Boudoux","doi":"10.1364/BOE.564589","DOIUrl":null,"url":null,"abstract":"<p><p>A novel method for measuring non-axial flow speed using optical techniques such as optical coherence tomography is introduced. The approach was based on the use of a modally-specific photonic lantern, which permits simultaneous probing of the sample with three distinct coherent spread functions. Transverse flow speed is measured from the ratio between the cross-correlation and autocorrelation of the signals. It achieved a 3 to 5 times higher accuracy than common autocorrelation approaches and measured flows as slow as 0.5 mm/s for an integration time of 1 second. Additionally, the method gives information on the flow's three-dimensional orientation, does not require information about the diffusion coefficient, and is more robust to bias errors such as a gradient in the axial flow velocity.</p>","PeriodicalId":8969,"journal":{"name":"Biomedical optics express","volume":"16 8","pages":"3395-3414"},"PeriodicalIF":3.2000,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339297/pdf/","citationCount":"0","resultStr":"{\"title\":\"Accurate flow speed measurement through correlation ratios using a mode-selective photonic lantern in optical coherence tomography.\",\"authors\":\"Raphaël Maltais-Tariant, Rodrigo Itzamna Becerra-Deana, Simon Brais-Brunet, Mathieu Dehaes, Caroline Boudoux\",\"doi\":\"10.1364/BOE.564589\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A novel method for measuring non-axial flow speed using optical techniques such as optical coherence tomography is introduced. The approach was based on the use of a modally-specific photonic lantern, which permits simultaneous probing of the sample with three distinct coherent spread functions. Transverse flow speed is measured from the ratio between the cross-correlation and autocorrelation of the signals. It achieved a 3 to 5 times higher accuracy than common autocorrelation approaches and measured flows as slow as 0.5 mm/s for an integration time of 1 second. Additionally, the method gives information on the flow's three-dimensional orientation, does not require information about the diffusion coefficient, and is more robust to bias errors such as a gradient in the axial flow velocity.</p>\",\"PeriodicalId\":8969,\"journal\":{\"name\":\"Biomedical optics express\",\"volume\":\"16 8\",\"pages\":\"3395-3414\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-07-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339297/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical optics express\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1364/BOE.564589\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical optics express","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1364/BOE.564589","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Accurate flow speed measurement through correlation ratios using a mode-selective photonic lantern in optical coherence tomography.
A novel method for measuring non-axial flow speed using optical techniques such as optical coherence tomography is introduced. The approach was based on the use of a modally-specific photonic lantern, which permits simultaneous probing of the sample with three distinct coherent spread functions. Transverse flow speed is measured from the ratio between the cross-correlation and autocorrelation of the signals. It achieved a 3 to 5 times higher accuracy than common autocorrelation approaches and measured flows as slow as 0.5 mm/s for an integration time of 1 second. Additionally, the method gives information on the flow's three-dimensional orientation, does not require information about the diffusion coefficient, and is more robust to bias errors such as a gradient in the axial flow velocity.
期刊介绍:
The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including:
Tissue optics and spectroscopy
Novel microscopies
Optical coherence tomography
Diffuse and fluorescence tomography
Photoacoustic and multimodal imaging
Molecular imaging and therapies
Nanophotonic biosensing
Optical biophysics/photobiology
Microfluidic optical devices
Vision research.