可见光催化菲菲啉合成的最新进展

IF 8.9 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Chinese Chemical Letters Pub Date : 2025-06-18 DOI:10.1016/j.cclet.2025.111485

Xia Mi , Chaoyang Wang , Jingyu Zhang , Remi Chauvin , Xiuling Cui

{"title":"可见光催化菲菲啉合成的最新进展","authors":"Xia Mi , Chaoyang Wang , Jingyu Zhang , Remi Chauvin , Xiuling Cui","doi":"10.1016/j.cclet.2025.111485","DOIUrl":null,"url":null,"abstract":"<div><div>Phenanthridine is a key structural motif in numerous natural products and biologically active compounds, making it an attractive target for pharmaceuticals and advanced materials. Recently, visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions, paving the way for new applications in synthetic and medicinal chemistry. This review highlights recent progress in the photochemical synthesis of phenanthridines, mainly focusing on various radical acceptors, including 2-isocyanobiaryls, cyanides, vinyl azides and vinyl benzotriazoles.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 11","pages":"Article 111485"},"PeriodicalIF":8.9000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recent progress in the visible-light-promoted synthesis of phenanthridines\",\"authors\":\"Xia Mi , Chaoyang Wang , Jingyu Zhang , Remi Chauvin , Xiuling Cui\",\"doi\":\"10.1016/j.cclet.2025.111485\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Phenanthridine is a key structural motif in numerous natural products and biologically active compounds, making it an attractive target for pharmaceuticals and advanced materials. Recently, visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions, paving the way for new applications in synthetic and medicinal chemistry. This review highlights recent progress in the photochemical synthesis of phenanthridines, mainly focusing on various radical acceptors, including 2-isocyanobiaryls, cyanides, vinyl azides and vinyl benzotriazoles.</div></div>\",\"PeriodicalId\":10088,\"journal\":{\"name\":\"Chinese Chemical Letters\",\"volume\":\"36 11\",\"pages\":\"Article 111485\"},\"PeriodicalIF\":8.9000,\"publicationDate\":\"2025-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Chemical Letters\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1001841725006680\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Chemical Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1001841725006680","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

菲苯胺是许多天然产物和生物活性化合物的关键结构基序，使其成为药物和先进材料的一个有吸引力的靶点。最近，通过自由基过程的可见光诱导环化已经成为在温和和环境友好的条件下构建这样一个核心的强大和可持续的策略，为合成和药物化学的新应用铺平了道路。本文综述了近年来菲并啶类化合物光化学合成的研究进展，重点介绍了各种自由基受体，包括2-异氰基、氰化物、乙烯基叠氮化物和乙烯基苯并三唑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Recent progress in the visible-light-promoted synthesis of phenanthridines

查看原文本刊更多论文

Recent progress in the visible-light-promoted synthesis of phenanthridines

Phenanthridine is a key structural motif in numerous natural products and biologically active compounds, making it an attractive target for pharmaceuticals and advanced materials. Recently, visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions, paving the way for new applications in synthetic and medicinal chemistry. This review highlights recent progress in the photochemical synthesis of phenanthridines, mainly focusing on various radical acceptors, including 2-isocyanobiaryls, cyanides, vinyl azides and vinyl benzotriazoles.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chinese Chemical Letters 化学-化学综合

CiteScore

14.10

自引率

15.40%

发文量

8969

审稿时长

1.6 months

期刊介绍： Chinese Chemical Letters (CCL) (ISSN 1001-8417) was founded in July 1990. The journal publishes preliminary accounts in the whole field of chemistry, including inorganic chemistry, organic chemistry, analytical chemistry, physical chemistry, polymer chemistry, applied chemistry, etc.Chinese Chemical Letters does not accept articles previously published or scheduled to be published. To verify originality, your article may be checked by the originality detection service CrossCheck.