一个保守的RNA基序引导dcl1介导的植物microRNA生物发生中的裂解

IF 13.6 1区生物学 Q1 PLANT SCIENCES

Nature Plants Pub Date : 2025-08-14 DOI:10.1038/s41477-025-02081-y

引用次数: 0

摘要

一个保守的GHR基序被证明在植物miRNA生物发生过程中指导dcl1介导的pre-miRNA的裂解。这一发现促进了我们对RNA加工机制的理解，并且由于该基序的切割导致已知非规范miRNA的产生，为miRNA的成熟和功能提供了见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A conserved RNA motif guides DCL1-mediated cleavage in plant microRNA biogenesis

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A conserved RNA motif guides DCL1-mediated cleavage in plant microRNA biogenesis

A conserved GHR motif is shown to guide the DCL1-mediated cleavage of pre-miRNAs during plant miRNA biogenesis. This discovery advances our understanding of the mechanisms underlying RNA processing and, as cleavage at this motif results in the production of known non-canonical miRNAs, offers insights into miRNA maturation and function.

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来源期刊

Nature Plants PLANT SCIENCES-

CiteScore

25.30

自引率

2.20%

发文量

196

期刊介绍： Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.