预测COVID-19医院床位占用的模块化方法

IF 5.4 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
Ruarai J Tobin, Camelia R Walker, Robert Moss, James M McCaw, David J Price, Freya M Shearer
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引用次数: 0

摘要

背景:监测医院病床上的COVID-19患者人数是澳大利亚该疾病实时监测战略的关键组成部分。从2021年到2023年,我们对床位占用情况进行了短期预测,以支持公共卫生决策。方法:建立预测新型冠状病毒病区和重症监护病房(ICU)床位数量的模型。该模型模拟了COVID-19患者在医院系统中的随机进展,并使用近似贝叶斯方法拟合报告的占用数。我们不直接建立感染动力学模型,而是将独立产生的病例发病率预测作为输入,从而使我们的模型能够从基础病例预测中独立开发出来。结果:在这里,我们评估了2022年3月至9月期间澳大利亚八个州和地区的21天病房和ICU入住率预测的表现。我们发现,在疫情高峰之前,预测平均倾向于向下,高峰后倾向于向上。在人口规模最大的司法管辖区,预测效果最好。结论:我们每周向国家决策委员会报告COVID-19医院负担预测,以支持澳大利亚的公共卫生应对。研究发现,我们用于预测临床负担的模块化方法既可以使我们的模型独立于潜在病例预测的模型开发,又可以通过我们的入住率预测来利用综合病例预测的性能优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A modular approach to forecasting COVID-19 hospital bed occupancy.

Background: Monitoring the number of COVID-19 patients in hospital beds was a critical component of Australia's real-time surveillance strategy for the disease. From 2021 to 2023, we produced short-term forecasts of bed occupancy to support public health decision-making.

Methods: We present a model for forecasting the number of ward and intensive care unit (ICU) beds occupied by COVID-19 cases. The model simulates the stochastic progression of COVID-19 patients through the hospital system and is fit to reported occupancy counts using an approximate Bayesian method. We do not directly model infection dynamics-instead, taking independently produced forecasts of case incidence as an input-enabling the independent development of our model from that of the underlying case forecast(s).

Results: Here, we evaluate the performance of 21-day forecasts of ward and ICU occupancy across Australia's eight states and territories produced across the period March and September 2022. We find forecasts are on average biased downwards immediately prior to epidemic peaks and biased upwards post-peak. Forecast performance is best in jurisdictions with the largest population sizes.

Conclusions: Our forecasts of COVID-19 hospital burden were reported weekly to national decision-making committees to support Australia's public health response. Our modular approach for forecasting clinical burden is found to enable both the independent development of our model from that of the underlying case forecast(s) and the performance benefits of an ensemble case forecast to be leveraged by our occupancy forecasts.

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