Stephanie Behme, Shiwei Zhou, Andrew Brown, Gary M Rothenberg
{"title":"未愈合溃疡的抗酸杆菌染色：皮肤龟分枝杆菌感染1例报告。","authors":"Stephanie Behme, Shiwei Zhou, Andrew Brown, Gary M Rothenberg","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cutaneous infections due to nontuberculous mycobacteria (NTM) are rare, and they can be challenging to treat, often requiring prolonged therapy with multiple antibiotics. Although recent literature challenges the idea of routine acid-fast bacilli (AFB) testing in diabetic foot infections, this report presents a case of Mycobacterium chelonae (M chelonae) infection in a patient with nonhealing ulceration.</p><p><strong>Case report: </strong>A 64-year-old female with no history of immunocompromise and no recent surgical history presented with a rapidly growing ulceration despite appropriate antibiotic therapy based on routine aerobic culture results. After AFB cultures were obtained, she was found to have NTM infection with M chelonae, and the ulceration was healed without recurrence after treatment for 4 months with linezolid and clarithromycin.</p><p><strong>Conclusion: </strong>This case highlights the potential inoculation of M chelonae, even in immunocompetent patients without known inoculation injury, and it highlights the value of AFB cultures in patients who do not progress with standard wound care therapies and routine aerobic cultures.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":"37 7","pages":"264-268"},"PeriodicalIF":1.1000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Acid-fast bacilli staining for nonhealing ulcers: a case report of cutaneous Mycobacterium chelonae infection.\",\"authors\":\"Stephanie Behme, Shiwei Zhou, Andrew Brown, Gary M Rothenberg\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Cutaneous infections due to nontuberculous mycobacteria (NTM) are rare, and they can be challenging to treat, often requiring prolonged therapy with multiple antibiotics. Although recent literature challenges the idea of routine acid-fast bacilli (AFB) testing in diabetic foot infections, this report presents a case of Mycobacterium chelonae (M chelonae) infection in a patient with nonhealing ulceration.</p><p><strong>Case report: </strong>A 64-year-old female with no history of immunocompromise and no recent surgical history presented with a rapidly growing ulceration despite appropriate antibiotic therapy based on routine aerobic culture results. After AFB cultures were obtained, she was found to have NTM infection with M chelonae, and the ulceration was healed without recurrence after treatment for 4 months with linezolid and clarithromycin.</p><p><strong>Conclusion: </strong>This case highlights the potential inoculation of M chelonae, even in immunocompetent patients without known inoculation injury, and it highlights the value of AFB cultures in patients who do not progress with standard wound care therapies and routine aerobic cultures.</p>\",\"PeriodicalId\":23752,\"journal\":{\"name\":\"Wounds : a compendium of clinical research and practice\",\"volume\":\"37 7\",\"pages\":\"264-268\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Wounds : a compendium of clinical research and practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wounds : a compendium of clinical research and practice","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Acid-fast bacilli staining for nonhealing ulcers: a case report of cutaneous Mycobacterium chelonae infection.
Background: Cutaneous infections due to nontuberculous mycobacteria (NTM) are rare, and they can be challenging to treat, often requiring prolonged therapy with multiple antibiotics. Although recent literature challenges the idea of routine acid-fast bacilli (AFB) testing in diabetic foot infections, this report presents a case of Mycobacterium chelonae (M chelonae) infection in a patient with nonhealing ulceration.
Case report: A 64-year-old female with no history of immunocompromise and no recent surgical history presented with a rapidly growing ulceration despite appropriate antibiotic therapy based on routine aerobic culture results. After AFB cultures were obtained, she was found to have NTM infection with M chelonae, and the ulceration was healed without recurrence after treatment for 4 months with linezolid and clarithromycin.
Conclusion: This case highlights the potential inoculation of M chelonae, even in immunocompetent patients without known inoculation injury, and it highlights the value of AFB cultures in patients who do not progress with standard wound care therapies and routine aerobic cultures.
期刊介绍：
Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies.
Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more.
Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.
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