进餐时间模式与女性心脏代谢健康的时间型特异性关联:一项横断面研究

IF 4.1 2区 医学 Q2 NUTRITION & DIETETICS
Azadeh Lesani, Neda Soveid, Cain C T Clark, Bahar Barkhidarian, Fatemeh Gholami, Mansooreh Sadat Mojani-Qomi
{"title":"进餐时间模式与女性心脏代谢健康的时间型特异性关联:一项横断面研究","authors":"Azadeh Lesani, Neda Soveid, Cain C T Clark, Bahar Barkhidarian, Fatemeh Gholami, Mansooreh Sadat Mojani-Qomi","doi":"10.1186/s12986-025-00985-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Although prior studies have examined meal timing and health, few have considered the impact of individual chronotypes and diurnal preference. This study explored how meal distribution and chronotype-morning (M-type) versus evening (E-type)- are associated with cardiometabolic health.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 574 women in Tehran, Iran. Dietary intake was assessed through three 24-hour recalls and chronotype was determined via the Morningness-Eveningness Questionnaire. Cardiometabolic markers-including blood pressure (BP), glucose, lipids, insulin, and high-sensitivity C-reactive protein (hs-CRP)-were measured.</p><p><strong>Results: </strong>In E-type individuals, higher breakfast energy intake was linearly associated with lower systolic [β 95% CI, -0.03 (-0.05 <sub>to</sub> -0.01)] and diastolic BP [-0.01 (-0.04 <sub>to</sub> -0.003)]. Afternoon energy intake was associated with lower BMI [-0.02 (-0.04 <sub>to</sub> -0.001)] and hs-CRP [-0.001 (-0.002 <sub>to</sub> -0.0006)] in E-type women. Additionally, U-shaped associations were found between breakfast intake and systolic BP (turning point: 23% of total energy intake (TEI)), and between afternoon intake and BMI (13% TEI) and hs-CRP (12% TEI). In contrast, higher dinner energy intake was linearly associated with greater BMI in the intermediate [-0.01 (-0.02 <sub>to</sub> -0.002)] and E-type group [0.05 (0.003 <sub>to</sub> 0.09)], respectively. Eating window was associated with higher fasting blood glucose [0.001 (0.002 <sub>to</sub> 0.003)] in E-type vs. M-type individuals.</p><p><strong>Conclusion: </strong>Aligning energy intake with wake-up time-rather than delaying meals-may benefit evening chronotypes prone to circadian misalignment. Moderate breakfast and afternoon intake, with lower dinner intake, was related to better cardiometabolic health. Accordingly, longitudinal studies are advocated.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":"22 1","pages":"96"},"PeriodicalIF":4.1000,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341138/pdf/","citationCount":"0","resultStr":"{\"title\":\"Chronotype-specific associations of meal timing patterns with cardiometabolic health in women: a cross-sectional study.\",\"authors\":\"Azadeh Lesani, Neda Soveid, Cain C T Clark, Bahar Barkhidarian, Fatemeh Gholami, Mansooreh Sadat Mojani-Qomi\",\"doi\":\"10.1186/s12986-025-00985-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Although prior studies have examined meal timing and health, few have considered the impact of individual chronotypes and diurnal preference. This study explored how meal distribution and chronotype-morning (M-type) versus evening (E-type)- are associated with cardiometabolic health.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 574 women in Tehran, Iran. Dietary intake was assessed through three 24-hour recalls and chronotype was determined via the Morningness-Eveningness Questionnaire. Cardiometabolic markers-including blood pressure (BP), glucose, lipids, insulin, and high-sensitivity C-reactive protein (hs-CRP)-were measured.</p><p><strong>Results: </strong>In E-type individuals, higher breakfast energy intake was linearly associated with lower systolic [β 95% CI, -0.03 (-0.05 <sub>to</sub> -0.01)] and diastolic BP [-0.01 (-0.04 <sub>to</sub> -0.003)]. Afternoon energy intake was associated with lower BMI [-0.02 (-0.04 <sub>to</sub> -0.001)] and hs-CRP [-0.001 (-0.002 <sub>to</sub> -0.0006)] in E-type women. Additionally, U-shaped associations were found between breakfast intake and systolic BP (turning point: 23% of total energy intake (TEI)), and between afternoon intake and BMI (13% TEI) and hs-CRP (12% TEI). In contrast, higher dinner energy intake was linearly associated with greater BMI in the intermediate [-0.01 (-0.02 <sub>to</sub> -0.002)] and E-type group [0.05 (0.003 <sub>to</sub> 0.09)], respectively. Eating window was associated with higher fasting blood glucose [0.001 (0.002 <sub>to</sub> 0.003)] in E-type vs. M-type individuals.</p><p><strong>Conclusion: </strong>Aligning energy intake with wake-up time-rather than delaying meals-may benefit evening chronotypes prone to circadian misalignment. Moderate breakfast and afternoon intake, with lower dinner intake, was related to better cardiometabolic health. Accordingly, longitudinal studies are advocated.</p>\",\"PeriodicalId\":19196,\"journal\":{\"name\":\"Nutrition & Metabolism\",\"volume\":\"22 1\",\"pages\":\"96\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2025-08-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341138/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrition & Metabolism\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12986-025-00985-2\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition & Metabolism","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12986-025-00985-2","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0

摘要

背景:虽然之前的研究已经研究了进餐时间和健康,但很少有人考虑到个体的睡眠类型和昼夜偏好的影响。这项研究探讨了膳食分布和时间类型——早上(m型)和晚上(e型)——与心脏代谢健康的关系。方法:对伊朗德黑兰574名妇女进行横断面研究。通过三次24小时回忆来评估饮食摄入量,并通过早晚性问卷来确定睡眠类型。测量心脏代谢指标,包括血压(BP)、葡萄糖、血脂、胰岛素和高敏c反应蛋白(hs-CRP)。结果:在e型个体中,较高的早餐能量摄入与较低的收缩压[β 95% CI, -0.03(-0.05至-0.01)]和舒张压[-0.01(-0.04至-0.003)]呈线性相关。在e型女性中,下午能量摄入与较低的BMI[-0.02(-0.04至-0.001)]和hs-CRP[-0.001(-0.002至-0.0006)]相关。此外,早餐摄入与收缩压(转折点:总能量摄入(TEI)的23%)、下午摄入与BMI (TEI的13%)和hs-CRP (TEI的12%)之间存在u型关联。相反,在中间型组[-0.01(-0.02 ~ -0.002)]和e型组[0.05(0.003 ~ 0.09)],较高的晚餐能量摄入分别与较高的BMI呈线性相关。在e型和m型个体中,进食窗口与较高的空腹血糖相关[0.001(0.002至0.003)]。结论:调整能量摄入与起床时间——而不是推迟进餐时间——可能有利于容易出现昼夜节律失调的晚上时间型。早餐和下午摄入适量,晚餐摄入较少,与更好的心脏代谢健康有关。因此,提倡纵向研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chronotype-specific associations of meal timing patterns with cardiometabolic health in women: a cross-sectional study.

Background: Although prior studies have examined meal timing and health, few have considered the impact of individual chronotypes and diurnal preference. This study explored how meal distribution and chronotype-morning (M-type) versus evening (E-type)- are associated with cardiometabolic health.

Methods: A cross-sectional study was conducted among 574 women in Tehran, Iran. Dietary intake was assessed through three 24-hour recalls and chronotype was determined via the Morningness-Eveningness Questionnaire. Cardiometabolic markers-including blood pressure (BP), glucose, lipids, insulin, and high-sensitivity C-reactive protein (hs-CRP)-were measured.

Results: In E-type individuals, higher breakfast energy intake was linearly associated with lower systolic [β 95% CI, -0.03 (-0.05 to -0.01)] and diastolic BP [-0.01 (-0.04 to -0.003)]. Afternoon energy intake was associated with lower BMI [-0.02 (-0.04 to -0.001)] and hs-CRP [-0.001 (-0.002 to -0.0006)] in E-type women. Additionally, U-shaped associations were found between breakfast intake and systolic BP (turning point: 23% of total energy intake (TEI)), and between afternoon intake and BMI (13% TEI) and hs-CRP (12% TEI). In contrast, higher dinner energy intake was linearly associated with greater BMI in the intermediate [-0.01 (-0.02 to -0.002)] and E-type group [0.05 (0.003 to 0.09)], respectively. Eating window was associated with higher fasting blood glucose [0.001 (0.002 to 0.003)] in E-type vs. M-type individuals.

Conclusion: Aligning energy intake with wake-up time-rather than delaying meals-may benefit evening chronotypes prone to circadian misalignment. Moderate breakfast and afternoon intake, with lower dinner intake, was related to better cardiometabolic health. Accordingly, longitudinal studies are advocated.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nutrition & Metabolism
Nutrition & Metabolism 医学-营养学
CiteScore
8.40
自引率
0.00%
发文量
78
审稿时长
4-8 weeks
期刊介绍: Nutrition & Metabolism publishes studies with a clear focus on nutrition and metabolism with applications ranging from nutrition needs, exercise physiology, clinical and population studies, as well as the underlying mechanisms in these aspects. The areas of interest for Nutrition & Metabolism encompass studies in molecular nutrition in the context of obesity, diabetes, lipedemias, metabolic syndrome and exercise physiology. Manuscripts related to molecular, cellular and human metabolism, nutrient sensing and nutrient–gene interactions are also in interest, as are submissions that have employed new and innovative strategies like metabolomics/lipidomics or other omic-based biomarkers to predict nutritional status and metabolic diseases. Key areas we wish to encourage submissions from include: -how diet and specific nutrients interact with genes, proteins or metabolites to influence metabolic phenotypes and disease outcomes; -the role of epigenetic factors and the microbiome in the pathogenesis of metabolic diseases and their influence on metabolic responses to diet and food components; -how diet and other environmental factors affect epigenetics and microbiota; the extent to which genetic and nongenetic factors modify personal metabolic responses to diet and food compositions and the mechanisms involved; -how specific biologic networks and nutrient sensing mechanisms attribute to metabolic variability.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信