伤口周围区域血氧饱和度作为慢性肢体缺血性患者伤口愈合预测指标的有效性。

IF 1.7 4区医学 Q3 DERMATOLOGY

Journal of wound care Pub Date : 2025-08-02 DOI:10.12968/jowc.2023.0042

Yu Kagaya, Norihiko Ohura, Yuki Morishige, Yuki Take-E, Mine Ozaki

{"title":"伤口周围区域血氧饱和度作为慢性肢体缺血性患者伤口愈合预测指标的有效性。","authors":"Yu Kagaya, Norihiko Ohura, Yuki Morishige, Yuki Take-E, Mine Ozaki","doi":"10.12968/jowc.2023.0042","DOIUrl":null,"url":null,"abstract":"Objective: To verify the utility and accuracy of periwound regional oxygen saturation (rSO2) as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia (CLTI), and compare the results with skin perfusion pressure (SPP) measurements.Method: Patients with hard-to-heal (chronic) toe wounds and CLTI, and who had undergone toe rSO2 (near wound), forefoot rSO2 and SPP measurements, were retrospectively selected. Following the measurements, the patients were treated conservatively, and the progress of wound healing was evaluated 28-91 days after the rSO2/SPP measurements. Toe wounds were classified into two groups: healing and non-healing. Receiver operating characteristic curves were created for rSO2/SPP to evaluate the accuracy of the wound healing prediction index, and the area under the curve (AUC) was also evaluated.Results: A total of 118 toes from 76 limbs were included in the evaluation and analysis. The AUC of periwound rSO2 was 0.938 (cut-off value: 44%; sensitivity: 0.955; specificity: 0.793). The AUC of plantar forefoot rSO2 and SPP were 0.789 and 0.786, respectively. The dorsal forefoot rSO2 and SPP demonstrated lower accuracy as wound healing predictors compared with the plantar side (AUC: 0.551 and 0.758, respectively).Conclusion: In this retrospective study, periwound rSO2 was a highly accurate predictor of toe wound healing in patients with CLTI. Both plantar forefoot rSO2 and SPP demonstrated moderate-to-high accuracy as predictors of toe wound healing, but less than that for periwound rSO2. Prospective studies in controlled populations are required. New devices that can measure periwound perfusion may provide more accurate wound healing predictions.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"580-588"},"PeriodicalIF":1.7000,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effectiveness of periwound regional oxygen saturation as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia.\",\"authors\":\"Yu Kagaya, Norihiko Ohura, Yuki Morishige, Yuki Take-E, Mine Ozaki\",\"doi\":\"10.12968/jowc.2023.0042\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To verify the utility and accuracy of periwound regional oxygen saturation (rSO2) as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia (CLTI), and compare the results with skin perfusion pressure (SPP) measurements.Method: Patients with hard-to-heal (chronic) toe wounds and CLTI, and who had undergone toe rSO2 (near wound), forefoot rSO2 and SPP measurements, were retrospectively selected. Following the measurements, the patients were treated conservatively, and the progress of wound healing was evaluated 28-91 days after the rSO2/SPP measurements. Toe wounds were classified into two groups: healing and non-healing. Receiver operating characteristic curves were created for rSO2/SPP to evaluate the accuracy of the wound healing prediction index, and the area under the curve (AUC) was also evaluated.Results: A total of 118 toes from 76 limbs were included in the evaluation and analysis. The AUC of periwound rSO2 was 0.938 (cut-off value: 44%; sensitivity: 0.955; specificity: 0.793). The AUC of plantar forefoot rSO2 and SPP were 0.789 and 0.786, respectively. The dorsal forefoot rSO2 and SPP demonstrated lower accuracy as wound healing predictors compared with the plantar side (AUC: 0.551 and 0.758, respectively).Conclusion: In this retrospective study, periwound rSO2 was a highly accurate predictor of toe wound healing in patients with CLTI. Both plantar forefoot rSO2 and SPP demonstrated moderate-to-high accuracy as predictors of toe wound healing, but less than that for periwound rSO2. Prospective studies in controlled populations are required. New devices that can measure periwound perfusion may provide more accurate wound healing predictions.\",\"PeriodicalId\":17590,\"journal\":{\"name\":\"Journal of wound care\",\"volume\":\"34 8\",\"pages\":\"580-588\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-08-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of wound care\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12968/jowc.2023.0042\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of wound care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12968/jowc.2023.0042","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的：验证伤口周围区域氧饱和度（rSO2）作为慢性肢体缺血性（CLTI）患者伤口愈合预测指标的实用性和准确性，并将结果与皮肤灌注压（SPP）测量结果进行比较。方法：回顾性选择难愈合（慢性）足趾创伤和CLTI患者，并进行足趾rSO2（近创面）、前足rSO2和SPP测量。测量后，对患者进行保守治疗，并在测量rSO2/SPP后28-91天评估伤口愈合进展。将脚趾伤口分为愈合和未愈合两组。建立rSO2/SPP受试者工作特征曲线，评估伤口愈合预测指标的准确性，并评估曲线下面积（AUC）。结果：76条肢体共118个足趾纳入评估分析。绕周rSO2的AUC为0.938(临界值为44%；灵敏度:0.955;特异性:0.793)。足底前足rSO2和SPP的AUC分别为0.789和0.786。与足底侧相比，前足背侧rSO2和SPP作为伤口愈合预测指标的准确性较低（AUC分别为0.551和0.758）。结论：在这项回顾性研究中，伤口周围的rSO2是CLTI患者脚趾伤口愈合的一个高度准确的预测指标。足底前足rSO2和SPP作为足趾创面愈合的预测指标均表现出中高的准确性，但对于足趾创面周围rSO2的预测精度较低。需要在对照人群中进行前瞻性研究。可以测量伤口周围灌注的新设备可能提供更准确的伤口愈合预测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Effectiveness of periwound regional oxygen saturation as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia.

Objective: To verify the utility and accuracy of periwound regional oxygen saturation (rSO₂) as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia (CLTI), and compare the results with skin perfusion pressure (SPP) measurements.

Method: Patients with hard-to-heal (chronic) toe wounds and CLTI, and who had undergone toe rSO₂ (near wound), forefoot rSO₂ and SPP measurements, were retrospectively selected. Following the measurements, the patients were treated conservatively, and the progress of wound healing was evaluated 28-91 days after the rSO₂/SPP measurements. Toe wounds were classified into two groups: healing and non-healing. Receiver operating characteristic curves were created for rSO₂/SPP to evaluate the accuracy of the wound healing prediction index, and the area under the curve (AUC) was also evaluated.

Results: A total of 118 toes from 76 limbs were included in the evaluation and analysis. The AUC of periwound rSO₂ was 0.938 (cut-off value: 44%; sensitivity: 0.955; specificity: 0.793). The AUC of plantar forefoot rSO₂ and SPP were 0.789 and 0.786, respectively. The dorsal forefoot rSO₂ and SPP demonstrated lower accuracy as wound healing predictors compared with the plantar side (AUC: 0.551 and 0.758, respectively).

Conclusion: In this retrospective study, periwound rSO₂ was a highly accurate predictor of toe wound healing in patients with CLTI. Both plantar forefoot rSO₂ and SPP demonstrated moderate-to-high accuracy as predictors of toe wound healing, but less than that for periwound rSO₂. Prospective studies in controlled populations are required. New devices that can measure periwound perfusion may provide more accurate wound healing predictions.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.