年龄≥55岁COPD患者DALY负担的全球时间趋势和预测:年龄-时期队列分析和前沿2021

IF 4.3 2区 环境科学与生态学 Q1 CONSTRUCTION & BUILDING TECHNOLOGY
Indoor air Pub Date : 2025-08-12 DOI:10.1155/ina/4696858
Ke-Jie He, Zijia Liu, Yun Kong, Guoyu Gong
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引用次数: 0

摘要

固体燃料造成的家庭空气污染是慢性阻塞性肺疾病(COPD)的一个重要因素。本研究采用全球疾病负担(GBD) 2021,对年龄≥55岁的高危人群HAPSF所致COPD负担进行研究,旨在填补老年人群暴露风险方面的研究空白。从1990年到2021年,HAPSF导致COPD的年龄标准化残疾调整生命年(DALY)率在所有五个社会人口指数(SDI)地区均有所下降,其中SDI高地区下降最为明显(AAPC: - 14.5%)。年龄-时期-队列(APC)模型显示出明显的趋势:净漂移在大多数地区显示出持续下降,除了低SDI地区,在75岁以后DALY率显著增加。此外,APC模型还揭示了性别和不平等问题:SDI中部地区男性的风险比始终高于女性,而其他SDI地区男性的风险比都要低。分解分析显示,流行病学变化——主要是由于清洁能源转型、改善医疗保健服务和公共卫生干预而减少HAPSF暴露——是DALYs下降的关键驱动因素(316.35%),超过了人口增长和老龄化带来的压力。前沿分析强调,萨摩亚、巴基斯坦和印度等国相对于其SDI水平表现不佳,表明迫切需要制定有针对性的政策。利用Nordpred模型进行的预测表明,从2022年到2044年,DALYs将继续下降,强调了持续进展的潜力。这项研究为减少由HAPSF引起的全球慢性阻塞性肺病负担提供了关键见解,强调了解决社会经济和性别问题以实现卫生公平的综合战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Global Temporal Trends and Projections of DALY Burden in COPD Patients Aged ≥ 55 Years: Age–Period–Cohort Analysis and Frontiers 2021

Global Temporal Trends and Projections of DALY Burden in COPD Patients Aged ≥ 55 Years: Age–Period–Cohort Analysis and Frontiers 2021

Household air pollution from solid fuels (HAPSF) is a significant contributor to chronic obstructive pulmonary disease (COPD). Using the Global Burden of Disease (GBD) 2021, this study focuses on the burden of COPD caused by HAPSF in high-risk individuals aged ≥ 55 years, aimed at filling the research gap concerning exposure risk in the elderly population. From 1990 to 2021, the age standardized disability-adjusted life year (DALY) rate for COPD due to HAPSF declined across all five sociodemographic index (SDI) regions, with the most pronounced reduction in high SDI areas (AAPC: −14.5%). The age–period–cohort (APC) model revealed distinct trends: net drift showed a continuous decline in most regions except low SDI areas, where DALY rates increased significantly after age 75. In addition, the APC model also reveals sex and inequality issues: the risk ratio of men in the middle SDI region is always higher than that of women, whereas the risk of men in all other SDI regions is lower. Decomposition analysis revealed that epidemiological shifts—primarily reduced HAPSF exposure due to cleaner energy transitions, improved healthcare access, and public health interventions—were the key drivers of declining DALYs (316.35%), outweighing pressures from population growth and aging. Frontier analysis highlighted countries such as Samoa, Pakistan, and India as underperformers relative to their SDI levels, signaling an urgent need for targeted policies. Projections using the Nordpred model suggest a continued decline in DALYs from 2022 to 2044, underscoring the potential for sustained progress. This study provides key insights into reducing the global burden of COPD caused by HAPSF, emphasizing a comprehensive strategy to address socioeconomic and sex issues to achieve health equity.

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来源期刊
Indoor air
Indoor air 环境科学-工程:环境
CiteScore
10.80
自引率
10.30%
发文量
175
审稿时长
3 months
期刊介绍: The quality of the environment within buildings is a topic of major importance for public health. Indoor Air provides a location for reporting original research results in the broad area defined by the indoor environment of non-industrial buildings. An international journal with multidisciplinary content, Indoor Air publishes papers reflecting the broad categories of interest in this field: health effects; thermal comfort; monitoring and modelling; source characterization; ventilation and other environmental control techniques. The research results present the basic information to allow designers, building owners, and operators to provide a healthy and comfortable environment for building occupants, as well as giving medical practitioners information on how to deal with illnesses related to the indoor environment.
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