Kalliopi Megari, Dimitra V. Katsarou, Evangelos Mantsos, Vasiliki Miliadi, Elina Kosmidou, Agathi Argyriadi, Soultana Papadopoulou, Alexandros Argyriadis, Eugenia. I. Toki, Maria Sofologi
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Quality of Life and Anxiety of Adolescents With Cancer and Their Parents: Neurodevelopmental Implications in Adolescence
Background
Cancer is one of the most lethal chronic diseases, which has been the reason for the majority of losses of lives globally. Adolescents with cancer experience a lower quality of life compared to both their healthy peers and adult patients.
Methods
In the present study, 237 adolescents and 460 parents were evaluated with measures of quality of life and anxiety.
Results
All patients showed lower performance on QoL and increased performance on anxiety measures. Regarding parents' QoL, although parents of all groups had low performance on all measures, parents of adolescents with leukaemia experience poor quality of life and increased levels of anxiety.
Conclusion
Adolescents and young adults with cancer are going through a turbulent period of their lives, not only due to their diagnosis and treatment process but also due to the physical and psychosocial changes and neurodevelopmental consequences of paediatric cancer and its treatment in adolescence.
期刊介绍：
International Journal of Developmental Neuroscience publishes original research articles and critical review papers on all fundamental and clinical aspects of nervous system development, renewal and regeneration, as well as on the effects of genetic and environmental perturbations of brain development and homeostasis leading to neurodevelopmental disorders and neurological conditions. Studies describing the involvement of stem cells in nervous system maintenance and disease (including brain tumours), stem cell-based approaches for the investigation of neurodegenerative diseases, roles of neuroinflammation in development and disease, and neuroevolution are also encouraged. Investigations using molecular, cellular, physiological, genetic and epigenetic approaches in model systems ranging from simple invertebrates to human iPSC-based 2D and 3D models are encouraged, as are studies using experimental models that provide behavioural or evolutionary insights. The journal also publishes Special Issues dealing with topics at the cutting edge of research edited by Guest Editors appointed by the Editor in Chief. A major aim of the journal is to facilitate the transfer of fundamental studies of nervous system development, maintenance, and disease to clinical applications. The journal thus intends to disseminate valuable information for both biologists and physicians. International Journal of Developmental Neuroscience is owned and supported by The International Society for Developmental Neuroscience (ISDN), an organization of scientists interested in advancing developmental neuroscience research in the broadest sense.
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