老年人社会孤立的变化和虚弱的风险：来自两个前瞻性队列的结果

IF 4.3

Experimental gerontology Pub Date : 2025-08-13 DOI:10.1016/j.exger.2025.112863

Fan Zhang , Chang Liu , Yan Bai , Min Cao

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引用次数: 0

摘要

目的探讨老年人社会孤立变化与偶发性虚弱之间的纵向关系。方法选取来自中国健康与退休纵向研究（CHARLS）和欧洲健康、老龄化和退休调查（SHARE）的成年人。来自CHARLS的3931名参与者和来自SHARE的15817名参与者年龄在60岁及以上，基线时身体不虚弱。社会隔离的评估采用CHARLS量表中的6个问题（得分≥3）和SHARE量表中的4个问题（得分≥2）。Rockwood脆弱指数≥25定义为虚弱。社会隔离的变化分为“没有隔离”、“严重隔离”、“解决隔离”和“持续隔离”。结果在CHARLS中，持续隔离与虚弱风险增加相关(危险比[HR]， 1.2；95%置信区间[95% CI]， 1.1 - 1.4)，但两者均未形成分离(HR, 1.1；95% CI, 1.0-1.3)也没有解决隔离(HR, 1.1；95% CI（0.9-1.2）显示有显著相关性。在SHARE中，持久隔离(HR, 1.4；95% CI, 1.2-1.6)和分离分离(HR, 1.3；95% CI, 1.0-1.6)与虚弱显著相关，而发达的隔离没有显著关联(HR, 1.1；95% ci, 1.0-1.2)。结论社会孤立程度的改变与老年人虚弱的发生率有显著关系。

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Change in social isolation and risk of frailty among older adults: results from two prospective cohorts

Objective

This study investigates the longitudinal association between changes in social isolation and incident frailty in older adults.

Methods

Older adults from the China Health and Retirement Longitudinal Study (CHARLS) and the Survey of Health, Ageing, and Retirement in Europe (SHARE). About 3931 participants from CHARLS and 15,817 participants from SHARE aged 60 years and older who were non-frail at baseline were included. Social isolation was assessed using six questions in CHARLS (score ≥ 3) and four questions in SHARE (score ≥ 2). Frailty was defined as Rockwood Frailty Index ≥25. Changes in social isolation were categorized as “no isolation,” “developed isolation,” “resolved isolation,” and “persistent isolation”.

Results

In CHARLS, persistent isolation was associated with an increased risk of frailty (hazard ratio [HR], 1.2; 95 % confidence interval [95 % CI], 1.1–1.4), while neither developed isolation (HR, 1.1; 95 % CI, 1.0–1.3) nor resolved isolation (HR, 1.1; 95 % CI, 0.9–1.2) showed significant associations. In SHARE, both persistent isolation (HR, 1.4; 95 % CI, 1.2–1.6) and resolved isolation (HR, 1.3; 95 % CI, 1.0–1.6) were significantly associated with frailty, whereas developed isolation showed no significant association (HR, 1.1; 95 % CI, 1.0–1.2).