{"title":"海洋来源真菌曲霉（Aspergillus sp.）天然产物抗癌活性综述。","authors":"Gulab Said","doi":"10.1016/j.prenap.2025.100334","DOIUrl":null,"url":null,"abstract":"<div><div>Marine derived fungi are rich sources of bioactive compounds. Among them, <em>Aspergillus</em> sp. are promising producers of marine bioactive compounds. The present review provides an overview of anticancer natural products that are produced by marine derived fungi <em>Aspergillus</em> sp. and the derivatives of some of them, covering the literature from 1997 to 2025. Subsequently, 185 natural products and their derivatives that have a broad range of potent anticancer activities against various cancer cell lines are stated in this review. Consequently, it is found that secondary metabolites derived from marine <em>Aspergillus</em> sp., showed a promising avenue for cancer treatment and offering unique mechanisms of action as well as potential advantages over the traditional chemotherapeutic agents.</div></div>","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"8 ","pages":"Article 100334"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A glance on the anticancer activities of natural products from marine derived fungi, Aspergillus sp.\",\"authors\":\"Gulab Said\",\"doi\":\"10.1016/j.prenap.2025.100334\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Marine derived fungi are rich sources of bioactive compounds. Among them, <em>Aspergillus</em> sp. are promising producers of marine bioactive compounds. The present review provides an overview of anticancer natural products that are produced by marine derived fungi <em>Aspergillus</em> sp. and the derivatives of some of them, covering the literature from 1997 to 2025. Subsequently, 185 natural products and their derivatives that have a broad range of potent anticancer activities against various cancer cell lines are stated in this review. Consequently, it is found that secondary metabolites derived from marine <em>Aspergillus</em> sp., showed a promising avenue for cancer treatment and offering unique mechanisms of action as well as potential advantages over the traditional chemotherapeutic agents.</div></div>\",\"PeriodicalId\":101014,\"journal\":{\"name\":\"Pharmacological Research - Natural Products\",\"volume\":\"8 \",\"pages\":\"Article 100334\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacological Research - Natural Products\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2950199725001946\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacological Research - Natural Products","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950199725001946","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A glance on the anticancer activities of natural products from marine derived fungi, Aspergillus sp.
Marine derived fungi are rich sources of bioactive compounds. Among them, Aspergillus sp. are promising producers of marine bioactive compounds. The present review provides an overview of anticancer natural products that are produced by marine derived fungi Aspergillus sp. and the derivatives of some of them, covering the literature from 1997 to 2025. Subsequently, 185 natural products and their derivatives that have a broad range of potent anticancer activities against various cancer cell lines are stated in this review. Consequently, it is found that secondary metabolites derived from marine Aspergillus sp., showed a promising avenue for cancer treatment and offering unique mechanisms of action as well as potential advantages over the traditional chemotherapeutic agents.
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