Shanshan Feng , Wan-Ting Cheng , Xing Li, Xiaofeng Luo
{"title":"中国老年人对艾滋病传播的贡献","authors":"Shanshan Feng , Wan-Ting Cheng , Xing Li, Xiaofeng Luo","doi":"10.1016/j.idm.2025.07.013","DOIUrl":null,"url":null,"abstract":"<div><div>In recent years, the number of HIV/AIDS cases shows an upward trend in China, particularly among the elderly, exerting severe effects on public health and social economy. This paper proposes an HIV/AIDS model incorporating sexual transmission and age structure to study the influence of the elderly on HIV/AIDS spread. Theoretically, the explicit expression for the basic reproduction number is obtained, the globally asymptotically stability of disease-free equilibrium and existence and uniqueness of boundary equilibrium are proved. Numerically, we verify the theoretical results. Based on HIV/AIDS data in Sichuan Province, China, four key parameters of the model are estimated. According to the estimated parameters, we find that homosexual transmission plays an important role in newly HIV/AIDS cases among the elderly in recent years. Sensitivity analysis also shows that homosexual transmission in the elderly has the greatest effect on the basic reproduction number. This study not only contributes to a comprehensive understanding of the dynamical spread process of HIV/AIDS but also provides valuable experience for other sexually transmitted diseases.</div></div>","PeriodicalId":36831,"journal":{"name":"Infectious Disease Modelling","volume":"10 4","pages":"Pages 1488-1506"},"PeriodicalIF":2.5000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Contributions of the elderly to the transmission of HIV/AIDS in China\",\"authors\":\"Shanshan Feng , Wan-Ting Cheng , Xing Li, Xiaofeng Luo\",\"doi\":\"10.1016/j.idm.2025.07.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>In recent years, the number of HIV/AIDS cases shows an upward trend in China, particularly among the elderly, exerting severe effects on public health and social economy. This paper proposes an HIV/AIDS model incorporating sexual transmission and age structure to study the influence of the elderly on HIV/AIDS spread. Theoretically, the explicit expression for the basic reproduction number is obtained, the globally asymptotically stability of disease-free equilibrium and existence and uniqueness of boundary equilibrium are proved. Numerically, we verify the theoretical results. Based on HIV/AIDS data in Sichuan Province, China, four key parameters of the model are estimated. According to the estimated parameters, we find that homosexual transmission plays an important role in newly HIV/AIDS cases among the elderly in recent years. Sensitivity analysis also shows that homosexual transmission in the elderly has the greatest effect on the basic reproduction number. This study not only contributes to a comprehensive understanding of the dynamical spread process of HIV/AIDS but also provides valuable experience for other sexually transmitted diseases.</div></div>\",\"PeriodicalId\":36831,\"journal\":{\"name\":\"Infectious Disease Modelling\",\"volume\":\"10 4\",\"pages\":\"Pages 1488-1506\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-08-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infectious Disease Modelling\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468042725000727\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious Disease Modelling","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468042725000727","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Contributions of the elderly to the transmission of HIV/AIDS in China
In recent years, the number of HIV/AIDS cases shows an upward trend in China, particularly among the elderly, exerting severe effects on public health and social economy. This paper proposes an HIV/AIDS model incorporating sexual transmission and age structure to study the influence of the elderly on HIV/AIDS spread. Theoretically, the explicit expression for the basic reproduction number is obtained, the globally asymptotically stability of disease-free equilibrium and existence and uniqueness of boundary equilibrium are proved. Numerically, we verify the theoretical results. Based on HIV/AIDS data in Sichuan Province, China, four key parameters of the model are estimated. According to the estimated parameters, we find that homosexual transmission plays an important role in newly HIV/AIDS cases among the elderly in recent years. Sensitivity analysis also shows that homosexual transmission in the elderly has the greatest effect on the basic reproduction number. This study not only contributes to a comprehensive understanding of the dynamical spread process of HIV/AIDS but also provides valuable experience for other sexually transmitted diseases.
期刊介绍:
Infectious Disease Modelling is an open access journal that undergoes peer-review. Its main objective is to facilitate research that combines mathematical modelling, retrieval and analysis of infection disease data, and public health decision support. The journal actively encourages original research that improves this interface, as well as review articles that highlight innovative methodologies relevant to data collection, informatics, and policy making in the field of public health.