{"title":"通过set诱导α-羰基自由基的形成催化羰基化合物α-C-H功能化","authors":"Anupam Kumar Singh , Sukalyan Bhadra","doi":"10.1039/d5cc03886c","DOIUrl":null,"url":null,"abstract":"<div><div>The catalytic α-functionalization of carbonyl compounds <em>via</em> SET induced formation of α-carbonyl radicals compares favorably with traditional electrophilic functionalization of enolates. The present review article showcases recent progress in the catalytic functionalization of ketones and carboxylic acid equivalents <em>via</em> single electron transfer (SET) induced formation of α-carbonyl radicals. Transition metal catalysed and photoredox-catalysed SET induced transformations of α-carbonyl radicals are primarily featured here.</div></div>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"61 74","pages":"Pages 14059-14072"},"PeriodicalIF":4.2000,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Catalytic α-C–H functionalization of carbonyl compounds via SET-induced formation of α-carbonyl radicals\",\"authors\":\"Anupam Kumar Singh , Sukalyan Bhadra\",\"doi\":\"10.1039/d5cc03886c\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The catalytic α-functionalization of carbonyl compounds <em>via</em> SET induced formation of α-carbonyl radicals compares favorably with traditional electrophilic functionalization of enolates. The present review article showcases recent progress in the catalytic functionalization of ketones and carboxylic acid equivalents <em>via</em> single electron transfer (SET) induced formation of α-carbonyl radicals. Transition metal catalysed and photoredox-catalysed SET induced transformations of α-carbonyl radicals are primarily featured here.</div></div>\",\"PeriodicalId\":67,\"journal\":{\"name\":\"Chemical Communications\",\"volume\":\"61 74\",\"pages\":\"Pages 14059-14072\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1359734525018269\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1359734525018269","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Catalytic α-C–H functionalization of carbonyl compounds via SET-induced formation of α-carbonyl radicals
The catalytic α-functionalization of carbonyl compounds via SET induced formation of α-carbonyl radicals compares favorably with traditional electrophilic functionalization of enolates. The present review article showcases recent progress in the catalytic functionalization of ketones and carboxylic acid equivalents via single electron transfer (SET) induced formation of α-carbonyl radicals. Transition metal catalysed and photoredox-catalysed SET induced transformations of α-carbonyl radicals are primarily featured here.
期刊介绍:
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.