{"title":"[肛门高度发育不良伴克罗恩病1例]。","authors":"Yuka Inaba, Kenji Tatsumi, Hirosuke Kuroki, Nao Obara, Akira Sugita, Hiroyuki Imaeda, Kazutaka Koganei","doi":"10.11405/nisshoshi.122.564","DOIUrl":null,"url":null,"abstract":"<p><p>A 47-year-old male patient with anal pain underwent a colonoscopy 12 years after Crohn's disease diagnosis. A biopsy from the protuberance of the anal canal revealed a well-differentiated adenocarcinoma. A reexamination of the histopathological specimen at our hospital revealed anal high grade dysplasia (HGD), thereby changing the initial diagnosis. A distal colon resection and rectal amputation were performed, and the final diagnosis of the resected specimen was anal canal HGD. While HGD associated with Crohn's disease is rare in Japan, this case suggests the importance of endoscopic examination, which might help in early detection of HGD.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 8","pages":"564-572"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Anal high grade dysplasia associated with Crohn's disease:a case report].\",\"authors\":\"Yuka Inaba, Kenji Tatsumi, Hirosuke Kuroki, Nao Obara, Akira Sugita, Hiroyuki Imaeda, Kazutaka Koganei\",\"doi\":\"10.11405/nisshoshi.122.564\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 47-year-old male patient with anal pain underwent a colonoscopy 12 years after Crohn's disease diagnosis. A biopsy from the protuberance of the anal canal revealed a well-differentiated adenocarcinoma. A reexamination of the histopathological specimen at our hospital revealed anal high grade dysplasia (HGD), thereby changing the initial diagnosis. A distal colon resection and rectal amputation were performed, and the final diagnosis of the resected specimen was anal canal HGD. While HGD associated with Crohn's disease is rare in Japan, this case suggests the importance of endoscopic examination, which might help in early detection of HGD.</p>\",\"PeriodicalId\":35808,\"journal\":{\"name\":\"Japanese Journal of Gastroenterology\",\"volume\":\"122 8\",\"pages\":\"564-572\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese Journal of Gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11405/nisshoshi.122.564\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11405/nisshoshi.122.564","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
[Anal high grade dysplasia associated with Crohn's disease:a case report].
A 47-year-old male patient with anal pain underwent a colonoscopy 12 years after Crohn's disease diagnosis. A biopsy from the protuberance of the anal canal revealed a well-differentiated adenocarcinoma. A reexamination of the histopathological specimen at our hospital revealed anal high grade dysplasia (HGD), thereby changing the initial diagnosis. A distal colon resection and rectal amputation were performed, and the final diagnosis of the resected specimen was anal canal HGD. While HGD associated with Crohn's disease is rare in Japan, this case suggests the importance of endoscopic examination, which might help in early detection of HGD.
期刊介绍:
The Journal of Gastroenterology, which is the official publication of the Japanese Society of Gastroenterology, publishes Original Articles (Alimentary Tract/Liver, Pancreas, and Biliary Tract), Review Articles, Letters to the Editors and other articles on all aspects of the field of gastroenterology. Significant contributions relating to basic research, theory, and practice are welcomed. These publications are designed to disseminate knowledge in this field to a worldwide audience, and accordingly, its editorial board has an international membership.