{"title":"经椎体前路治疗对侧C7神经易位治疗中枢性上肢麻痹的临床疗效分析","authors":"Shichang Guo, Bo Zhang, Xiaohui Liu, Jiabo Xiao, Binhong Li, Wandong Ma, Jinsheng Kang, Changzheng Dong","doi":"10.1080/00207454.2025.2544803","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical efficacy of the transvertebral anterior approach to contralateral C7 nerve translocation for treating patients with upper limb spastic hemiparesis caused by central nerve injury.</p><p><strong>Methods: </strong>Clinical data from 30 patients with central upper limb spastic hemiplegia were included in the study. All patients underwent rehabilitation exercises before surgery. As no significant improvement in motor function or muscle tone of the paralyzed upper limb was observed, contralateral C7 nerve translocation was performed. Changes in motor function of the paralyzed upper limb were assessed using the Fugl-Meyer Motor Function Assessment Scale (FMA) and Brunnstrom Staging Scale (BSS). Changes in muscle tone were evaluated using the Modified Ashworth Spasticity Rating Scale (MAS). Generalized estimating equation (GEE) analysis was performed using the preoperative FMA, BSS, and MAS scores as baseline values to assess improvements in motor function and muscle tone at 6 and 12 months postoperatively.</p><p><strong>Results: </strong>Significant differences were observed in motor function (FMA score and BSS stage) and muscle tone (MAS score) of the paralyzed upper limb at 6 and 12 months post-surgery compared to baseline (<i>p</i> < 0.05) in 30 patients. Recovery of the paralyzed upper limb showed a time-dependent cumulative effect, with greater improvement observed at 12 months post-surgery than at 6 months. Recovery of limb function exhibited progressive improvement from the proximal to the distal end.</p><p><strong>Conclusion: </strong>Contralateral C7 nerve translocation helps improve central upper limb spastic paralysis and reduce muscle spasticity, thereby enhancing upper limb motor function.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"1-9"},"PeriodicalIF":1.5000,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of the clinical effects of the transvertebral anterior approach for contralateral C7 nerve translocation in treating Central upper limb paralysis: a retrospective study.\",\"authors\":\"Shichang Guo, Bo Zhang, Xiaohui Liu, Jiabo Xiao, Binhong Li, Wandong Ma, Jinsheng Kang, Changzheng Dong\",\"doi\":\"10.1080/00207454.2025.2544803\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To investigate the clinical efficacy of the transvertebral anterior approach to contralateral C7 nerve translocation for treating patients with upper limb spastic hemiparesis caused by central nerve injury.</p><p><strong>Methods: </strong>Clinical data from 30 patients with central upper limb spastic hemiplegia were included in the study. All patients underwent rehabilitation exercises before surgery. As no significant improvement in motor function or muscle tone of the paralyzed upper limb was observed, contralateral C7 nerve translocation was performed. Changes in motor function of the paralyzed upper limb were assessed using the Fugl-Meyer Motor Function Assessment Scale (FMA) and Brunnstrom Staging Scale (BSS). Changes in muscle tone were evaluated using the Modified Ashworth Spasticity Rating Scale (MAS). Generalized estimating equation (GEE) analysis was performed using the preoperative FMA, BSS, and MAS scores as baseline values to assess improvements in motor function and muscle tone at 6 and 12 months postoperatively.</p><p><strong>Results: </strong>Significant differences were observed in motor function (FMA score and BSS stage) and muscle tone (MAS score) of the paralyzed upper limb at 6 and 12 months post-surgery compared to baseline (<i>p</i> < 0.05) in 30 patients. Recovery of the paralyzed upper limb showed a time-dependent cumulative effect, with greater improvement observed at 12 months post-surgery than at 6 months. Recovery of limb function exhibited progressive improvement from the proximal to the distal end.</p><p><strong>Conclusion: </strong>Contralateral C7 nerve translocation helps improve central upper limb spastic paralysis and reduce muscle spasticity, thereby enhancing upper limb motor function.</p>\",\"PeriodicalId\":14161,\"journal\":{\"name\":\"International Journal of Neuroscience\",\"volume\":\" \",\"pages\":\"1-9\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-08-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Neuroscience\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/00207454.2025.2544803\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00207454.2025.2544803","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Analysis of the clinical effects of the transvertebral anterior approach for contralateral C7 nerve translocation in treating Central upper limb paralysis: a retrospective study.
Objective: To investigate the clinical efficacy of the transvertebral anterior approach to contralateral C7 nerve translocation for treating patients with upper limb spastic hemiparesis caused by central nerve injury.
Methods: Clinical data from 30 patients with central upper limb spastic hemiplegia were included in the study. All patients underwent rehabilitation exercises before surgery. As no significant improvement in motor function or muscle tone of the paralyzed upper limb was observed, contralateral C7 nerve translocation was performed. Changes in motor function of the paralyzed upper limb were assessed using the Fugl-Meyer Motor Function Assessment Scale (FMA) and Brunnstrom Staging Scale (BSS). Changes in muscle tone were evaluated using the Modified Ashworth Spasticity Rating Scale (MAS). Generalized estimating equation (GEE) analysis was performed using the preoperative FMA, BSS, and MAS scores as baseline values to assess improvements in motor function and muscle tone at 6 and 12 months postoperatively.
Results: Significant differences were observed in motor function (FMA score and BSS stage) and muscle tone (MAS score) of the paralyzed upper limb at 6 and 12 months post-surgery compared to baseline (p < 0.05) in 30 patients. Recovery of the paralyzed upper limb showed a time-dependent cumulative effect, with greater improvement observed at 12 months post-surgery than at 6 months. Recovery of limb function exhibited progressive improvement from the proximal to the distal end.
Conclusion: Contralateral C7 nerve translocation helps improve central upper limb spastic paralysis and reduce muscle spasticity, thereby enhancing upper limb motor function.
期刊介绍:
The International Journal of Neuroscience publishes original research articles, reviews, brief scientific reports, case studies, letters to the editor and book reviews concerned with problems of the nervous system and related clinical studies, epidemiology, neuropathology, medical and surgical treatment options and outcomes, neuropsychology and other topics related to the research and care of persons with neurologic disorders. The focus of the journal is clinical and transitional research. Topics covered include but are not limited to: ALS, ataxia, autism, brain tumors, child neurology, demyelinating diseases, epilepsy, genetics, headache, lysosomal storage disease, mitochondrial dysfunction, movement disorders, multiple sclerosis, myopathy, neurodegenerative diseases, neuromuscular disorders, neuropharmacology, neuropsychiatry, neuropsychology, pain, sleep disorders, stroke, and other areas related to the neurosciences.