经椎体前路治疗对侧C7神经易位治疗中枢性上肢麻痹的临床疗效分析

IF 1.5 4区 医学 Q4 NEUROSCIENCES
Shichang Guo, Bo Zhang, Xiaohui Liu, Jiabo Xiao, Binhong Li, Wandong Ma, Jinsheng Kang, Changzheng Dong
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引用次数: 0

摘要

目的:探讨经椎体前路对侧C7神经移位治疗中枢神经损伤所致上肢痉挛性偏瘫的临床疗效。方法:对30例中枢性上肢痉挛性偏瘫患者的临床资料进行分析。所有患者在手术前平均进行了21.00(27.00)个月的康复训练。由于麻痹上肢的运动功能或肌肉张力未见明显改善,因此进行了对侧C7神经移位。采用Fugl-Meyer运动功能评估量表(FMA)和Brunnstrom分期量表(BSS)评估瘫痪上肢运动功能的变化。相反,使用改良Ashworth痉挛评定量表(MAS)评估肌肉张力的变化。采用麻痹上肢的术前FMA、BSS和MAS评分作为基线值,进行广义估计方程(GEE)分析,评估术后6个月和12个月运动功能和肌肉张力的改善情况。结果:术后6个月和12个月瘫痪上肢运动功能(FMA评分、BSS分期)和肌张力(MAS评分)与基线比较均有显著差异(P)。结论:对侧C7神经易位有助于改善中枢性上肢痉挛性麻痹,减轻肌肉痉挛,从而增强上肢运动功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of the clinical effects of the transvertebral anterior approach for contralateral C7 nerve translocation in treating Central upper limb paralysis: a retrospective study.

Objective: To investigate the clinical efficacy of the transvertebral anterior approach to contralateral C7 nerve translocation for treating patients with upper limb spastic hemiparesis caused by central nerve injury.

Methods: Clinical data from 30 patients with central upper limb spastic hemiplegia were included in the study. All patients underwent rehabilitation exercises before surgery. As no significant improvement in motor function or muscle tone of the paralyzed upper limb was observed, contralateral C7 nerve translocation was performed. Changes in motor function of the paralyzed upper limb were assessed using the Fugl-Meyer Motor Function Assessment Scale (FMA) and Brunnstrom Staging Scale (BSS). Changes in muscle tone were evaluated using the Modified Ashworth Spasticity Rating Scale (MAS). Generalized estimating equation (GEE) analysis was performed using the preoperative FMA, BSS, and MAS scores as baseline values to assess improvements in motor function and muscle tone at 6 and 12 months postoperatively.

Results: Significant differences were observed in motor function (FMA score and BSS stage) and muscle tone (MAS score) of the paralyzed upper limb at 6 and 12 months post-surgery compared to baseline (p < 0.05) in 30 patients. Recovery of the paralyzed upper limb showed a time-dependent cumulative effect, with greater improvement observed at 12 months post-surgery than at 6 months. Recovery of limb function exhibited progressive improvement from the proximal to the distal end.

Conclusion: Contralateral C7 nerve translocation helps improve central upper limb spastic paralysis and reduce muscle spasticity, thereby enhancing upper limb motor function.

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来源期刊
CiteScore
5.10
自引率
0.00%
发文量
132
审稿时长
2 months
期刊介绍: The International Journal of Neuroscience publishes original research articles, reviews, brief scientific reports, case studies, letters to the editor and book reviews concerned with problems of the nervous system and related clinical studies, epidemiology, neuropathology, medical and surgical treatment options and outcomes, neuropsychology and other topics related to the research and care of persons with neurologic disorders.  The focus of the journal is clinical and transitional research. Topics covered include but are not limited to: ALS, ataxia, autism, brain tumors, child neurology, demyelinating diseases, epilepsy, genetics, headache, lysosomal storage disease, mitochondrial dysfunction, movement disorders, multiple sclerosis, myopathy, neurodegenerative diseases, neuromuscular disorders, neuropharmacology, neuropsychiatry, neuropsychology, pain, sleep disorders, stroke, and other areas related to the neurosciences.
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