Aarushi S. Negi, Shreesh Karjagi, Laura Parisi, Kerry W. Daley, Annie K. Abay, Aryaman S. Gala, Kevin B. Wilkins, Shannon L. Hoffman, Margaret S. Ferris, Hengameh Zahed, Gaurav M. Chattree, Bianca Palushaj, Helen M. Bronte-Stewart
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Remote real time digital monitoring fills a critical gap in the management of Parkinson’s disease
People with Parkinson’s disease (PWP) face significant gaps in care. Limited neurologist access, infrequent clinic visits, and inadequate symptom measurement culminate in suboptimal therapy and high morbidity. Quantitative Digitography (QDG) provides validated, digital metrics of the three cardinal motor signs in Parkinson’s disease (PD) in real-time from 30 seconds of a mobility task on a digitography device and can be used remotely or in clinical settings. This study demonstrates the feasibility and clinical relevance of 30-day remote QDG monitoring. Participants showed excellent compliance and found the system easy to use. The QDG Mobility Score demonstrated meaningful correlation with Activities of Daily Living (ADLs), captured motor complexities across a broad PD duration, and tracked motor changes from small therapy adjustments. QDG offers providers and PWP an accessible, objective, and real-time tool to remotely monitor motor symptoms, optimize treatment, and address care gaps created by infrequent clinic visits and subjective symptom assessment.
期刊介绍:
npj Parkinson's Disease is a comprehensive open access journal that covers a wide range of research areas related to Parkinson's disease. It publishes original studies in basic science, translational research, and clinical investigations. The journal is dedicated to advancing our understanding of Parkinson's disease by exploring various aspects such as anatomy, etiology, genetics, cellular and molecular physiology, neurophysiology, epidemiology, and therapeutic development. By providing free and immediate access to the scientific and Parkinson's disease community, npj Parkinson's Disease promotes collaboration and knowledge sharing among researchers and healthcare professionals.