{"title":"[从耳朵到鼻咽的微生物群]。","authors":"Achim G Beule","doi":"10.1007/s00106-025-01660-x","DOIUrl":null,"url":null,"abstract":"<p><p>The results of a scoping review on the current state of scientific knowledge in relation to the various anatomical areas from the nasopharynx to the ear are presented. In brief, foreign bodies in the area of the outer ear (hearing aids, piercings) change the microbiome and favor a moist environment. Middle ear infections also lead to changes in the fecal microbiome. Chronic middle ear effusions with otitis media are characterized by Corynebacteria in the nasopharynx. Diseases of the lower respiratory tract are associated with a reduction in diversity in the microbiome of tympanic effusions. Biofilms in the middle ear are associated with severe conductive hearing loss. In patients with a cholesteatoma, an altered middle ear microbiome could also be detected on the opposite side. Both protective and risk-increasing factors of the gut microbiome have been reported for sensorineural hearing loss. The relationship between the microbiome of the nasopharynx and the ear is heterogeneous depending on the underlying disease. In particular, the ability to influence hearing function through diet and the association with the gut microbiome also shed new light on diet as a preventive option for ENT specialists.</p>","PeriodicalId":55052,"journal":{"name":"Hno","volume":" ","pages":"615-621"},"PeriodicalIF":1.3000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The microbiome from ear to nasopharynx].\",\"authors\":\"Achim G Beule\",\"doi\":\"10.1007/s00106-025-01660-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The results of a scoping review on the current state of scientific knowledge in relation to the various anatomical areas from the nasopharynx to the ear are presented. In brief, foreign bodies in the area of the outer ear (hearing aids, piercings) change the microbiome and favor a moist environment. Middle ear infections also lead to changes in the fecal microbiome. Chronic middle ear effusions with otitis media are characterized by Corynebacteria in the nasopharynx. Diseases of the lower respiratory tract are associated with a reduction in diversity in the microbiome of tympanic effusions. Biofilms in the middle ear are associated with severe conductive hearing loss. In patients with a cholesteatoma, an altered middle ear microbiome could also be detected on the opposite side. Both protective and risk-increasing factors of the gut microbiome have been reported for sensorineural hearing loss. The relationship between the microbiome of the nasopharynx and the ear is heterogeneous depending on the underlying disease. In particular, the ability to influence hearing function through diet and the association with the gut microbiome also shed new light on diet as a preventive option for ENT specialists.</p>\",\"PeriodicalId\":55052,\"journal\":{\"name\":\"Hno\",\"volume\":\" \",\"pages\":\"615-621\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hno\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00106-025-01660-x\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/11 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hno","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00106-025-01660-x","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/11 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
The results of a scoping review on the current state of scientific knowledge in relation to the various anatomical areas from the nasopharynx to the ear are presented. In brief, foreign bodies in the area of the outer ear (hearing aids, piercings) change the microbiome and favor a moist environment. Middle ear infections also lead to changes in the fecal microbiome. Chronic middle ear effusions with otitis media are characterized by Corynebacteria in the nasopharynx. Diseases of the lower respiratory tract are associated with a reduction in diversity in the microbiome of tympanic effusions. Biofilms in the middle ear are associated with severe conductive hearing loss. In patients with a cholesteatoma, an altered middle ear microbiome could also be detected on the opposite side. Both protective and risk-increasing factors of the gut microbiome have been reported for sensorineural hearing loss. The relationship between the microbiome of the nasopharynx and the ear is heterogeneous depending on the underlying disease. In particular, the ability to influence hearing function through diet and the association with the gut microbiome also shed new light on diet as a preventive option for ENT specialists.
期刊介绍:
HNO is an internationally recognized journal and addresses all ENT specialists in practices and clinics dealing with all aspects of ENT medicine, e.g. prevention, diagnostic methods, complication management, modern therapy strategies and surgical procedures.
Review articles provide an overview on selected topics and offer the reader a summary of current findings from all fields of ENT medicine.
Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange.
Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies.
Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.