Bogdan Andrei Bumbu, Mădălina Anca Moldovan, Iuliu George Moldovan, Alexandru Iosif Precup, Raluca Ortensia Iurcov
{"title":"多形腺癌:文献回顾和一个不常见解剖区域的病例介绍。","authors":"Bogdan Andrei Bumbu, Mădălina Anca Moldovan, Iuliu George Moldovan, Alexandru Iosif Precup, Raluca Ortensia Iurcov","doi":"10.15386/mpr-2882","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Polymorphous adenocarcinoma (PAC) is a type of salivary gland tumor that is rare and diverse in morphology. It is typically found in the minor salivary glands, with the palate being the most common location. However, this tumor is often misunderstood, underdiagnosed, and controversial in nomenclature. Its low-grade behavior may be unpredictable, making it challenging to manage.</p><p><strong>Case report: </strong>In this paper, we detail a case of PAC that developed in the buccal mucosa, which is a less common anatomical location. We discuss the patient's clinical presentation, imaging findings, histological examination results, as well as the surgical treatment and follow-up outcomes. We also examine relevant literature related to the topic to provide a comprehensive understanding of this rare case.</p><p><strong>Conclusions: </strong>Although complete surgical excision is the primary management for PAC, there is no gold standard treatment for it. It is crucial to follow up on patients with PAC in the long term, as recurrences, lymph nodes, and distant metastasis, even rare, may impair the prognosis in certain patients.</p>","PeriodicalId":18438,"journal":{"name":"Medicine and Pharmacy Reports","volume":"98 3","pages":"403-408"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334239/pdf/","citationCount":"0","resultStr":"{\"title\":\"Polymorphous adenocarcinoma: a review of the literature and presentation of a case in an uncommon anatomical area.\",\"authors\":\"Bogdan Andrei Bumbu, Mădălina Anca Moldovan, Iuliu George Moldovan, Alexandru Iosif Precup, Raluca Ortensia Iurcov\",\"doi\":\"10.15386/mpr-2882\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Polymorphous adenocarcinoma (PAC) is a type of salivary gland tumor that is rare and diverse in morphology. It is typically found in the minor salivary glands, with the palate being the most common location. However, this tumor is often misunderstood, underdiagnosed, and controversial in nomenclature. Its low-grade behavior may be unpredictable, making it challenging to manage.</p><p><strong>Case report: </strong>In this paper, we detail a case of PAC that developed in the buccal mucosa, which is a less common anatomical location. We discuss the patient's clinical presentation, imaging findings, histological examination results, as well as the surgical treatment and follow-up outcomes. We also examine relevant literature related to the topic to provide a comprehensive understanding of this rare case.</p><p><strong>Conclusions: </strong>Although complete surgical excision is the primary management for PAC, there is no gold standard treatment for it. It is crucial to follow up on patients with PAC in the long term, as recurrences, lymph nodes, and distant metastasis, even rare, may impair the prognosis in certain patients.</p>\",\"PeriodicalId\":18438,\"journal\":{\"name\":\"Medicine and Pharmacy Reports\",\"volume\":\"98 3\",\"pages\":\"403-408\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334239/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicine and Pharmacy Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15386/mpr-2882\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine and Pharmacy Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15386/mpr-2882","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Polymorphous adenocarcinoma: a review of the literature and presentation of a case in an uncommon anatomical area.
Background: Polymorphous adenocarcinoma (PAC) is a type of salivary gland tumor that is rare and diverse in morphology. It is typically found in the minor salivary glands, with the palate being the most common location. However, this tumor is often misunderstood, underdiagnosed, and controversial in nomenclature. Its low-grade behavior may be unpredictable, making it challenging to manage.
Case report: In this paper, we detail a case of PAC that developed in the buccal mucosa, which is a less common anatomical location. We discuss the patient's clinical presentation, imaging findings, histological examination results, as well as the surgical treatment and follow-up outcomes. We also examine relevant literature related to the topic to provide a comprehensive understanding of this rare case.
Conclusions: Although complete surgical excision is the primary management for PAC, there is no gold standard treatment for it. It is crucial to follow up on patients with PAC in the long term, as recurrences, lymph nodes, and distant metastasis, even rare, may impair the prognosis in certain patients.