{"title":"螺旋藻强化沙拉酱对高血压患者身体成分和人体测量指标的影响:一项双盲随机安慰剂对照试验。","authors":"Elnaz Ghaem Far, Siavash Babajafari, Zohreh Ghaem Far, Salman Mohammadi, Mehran Nouri, Javad Kojuri, Elham Ashrafi-Dehkordi, Mohammad Hossein Rahmani, Seyed Mohammad Mazloomi","doi":"10.22088/cjim.16.3.553","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have demonstrated that improving anthropometric indices through a healthy diet and exercise can aid individuals with high blood pressure. Additionally, research suggests that consuming Spirulina, a type of microalga, could positively impact body composition and anthropometric indices. The purpose of this study was to determine the effects of spirulina-fortified salad dressing on anthropometric indices and body composition in patients with hypertension.</p><p><strong>Methods: </strong>Forty-eight (19 men and 22 women) patients with hypertension randomly received either spirulina-fortified salad dressing containing 2 gr spirulina (SSD, n = 22) or a placebo salad dressing (PSD, n = 19) daily for eight weeks. This study was registered at https://www.irct.ir/ (the Iranian registry of clinical trials identifier: IRCT20200404046940N1).</p><p><strong>Results: </strong>There was a change in body composition and anthropometric indices from baseline to 8 weeks. We observed that the mean change±SD of waist circumference after the SSD intervention (-2.86±4.02 cm) was significantly different from that of the PSD intervention (0.38±9.47 cm). Although no between-group difference was observed, a statistically significant reduction in body fat-free mass (FFM) occurred in the PSD group after the intervention. Meanwhile, within-group mean change±SD of body fat-free mass (FFM, 1.04±5.39 kg) and body fat mass (FM, -0.73±1.83 kg) was significant only in the SSD group. However, no significance between-group difference was observed in terms of FFM and FM changes.</p><p><strong>Conclusion: </strong>The present study's findings suggest that consuming spirulina-fortified dressing can improve the status of risk factors associated with hypertension and cardiovascular diseases.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"16 3","pages":"553-561"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329358/pdf/","citationCount":"0","resultStr":"{\"title\":\"Spirulina-fortified salad dressing on body composition and anthropometric indices in hypertensive patients: A tipple-blind randomized placebo-controlled trial.\",\"authors\":\"Elnaz Ghaem Far, Siavash Babajafari, Zohreh Ghaem Far, Salman Mohammadi, Mehran Nouri, Javad Kojuri, Elham Ashrafi-Dehkordi, Mohammad Hossein Rahmani, Seyed Mohammad Mazloomi\",\"doi\":\"10.22088/cjim.16.3.553\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Numerous studies have demonstrated that improving anthropometric indices through a healthy diet and exercise can aid individuals with high blood pressure. Additionally, research suggests that consuming Spirulina, a type of microalga, could positively impact body composition and anthropometric indices. The purpose of this study was to determine the effects of spirulina-fortified salad dressing on anthropometric indices and body composition in patients with hypertension.</p><p><strong>Methods: </strong>Forty-eight (19 men and 22 women) patients with hypertension randomly received either spirulina-fortified salad dressing containing 2 gr spirulina (SSD, n = 22) or a placebo salad dressing (PSD, n = 19) daily for eight weeks. This study was registered at https://www.irct.ir/ (the Iranian registry of clinical trials identifier: IRCT20200404046940N1).</p><p><strong>Results: </strong>There was a change in body composition and anthropometric indices from baseline to 8 weeks. We observed that the mean change±SD of waist circumference after the SSD intervention (-2.86±4.02 cm) was significantly different from that of the PSD intervention (0.38±9.47 cm). Although no between-group difference was observed, a statistically significant reduction in body fat-free mass (FFM) occurred in the PSD group after the intervention. Meanwhile, within-group mean change±SD of body fat-free mass (FFM, 1.04±5.39 kg) and body fat mass (FM, -0.73±1.83 kg) was significant only in the SSD group. However, no significance between-group difference was observed in terms of FFM and FM changes.</p><p><strong>Conclusion: </strong>The present study's findings suggest that consuming spirulina-fortified dressing can improve the status of risk factors associated with hypertension and cardiovascular diseases.</p>\",\"PeriodicalId\":9646,\"journal\":{\"name\":\"Caspian Journal of Internal Medicine\",\"volume\":\"16 3\",\"pages\":\"553-561\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329358/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Caspian Journal of Internal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22088/cjim.16.3.553\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Caspian Journal of Internal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22088/cjim.16.3.553","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
背景:大量研究表明,通过健康饮食和运动改善人体测量指标可以帮助高血压患者。此外,研究表明,食用螺旋藻(一种微藻)可能对身体成分和人体测量指标产生积极影响。本研究的目的是确定螺旋藻强化沙拉酱对高血压患者人体测量指标和身体成分的影响。方法:48例高血压患者(19男22女)随机接受含有2克螺旋藻的螺旋藻强化沙拉酱(SSD, n = 22)或安慰剂沙拉酱(PSD, n = 19),每天8周。本研究注册于https://www.irct.ir/(伊朗临床试验注册编号:IRCT20200404046940N1)。结果:从基线到8周,身体成分和人体测量指标发生了变化。我们观察到,SSD干预后的腰围平均变化±SD(-2.86±4.02 cm)与PSD干预后的腰围平均变化(0.38±9.47 cm)有显著差异。虽然没有观察到组间差异,但干预后PSD组的体脂质量(FFM)有统计学意义上的显著降低。同时,体脂质量(FFM, 1.04±5.39 kg)和体脂质量(FM, -0.73±1.83 kg)的组内平均值变化±SD仅在SSD组有统计学意义。然而,在FFM和FM变化方面,组间无显著差异。结论:食用螺旋藻强化敷料可改善高血压和心血管疾病相关危险因素的状态。
Spirulina-fortified salad dressing on body composition and anthropometric indices in hypertensive patients: A tipple-blind randomized placebo-controlled trial.
Background: Numerous studies have demonstrated that improving anthropometric indices through a healthy diet and exercise can aid individuals with high blood pressure. Additionally, research suggests that consuming Spirulina, a type of microalga, could positively impact body composition and anthropometric indices. The purpose of this study was to determine the effects of spirulina-fortified salad dressing on anthropometric indices and body composition in patients with hypertension.
Methods: Forty-eight (19 men and 22 women) patients with hypertension randomly received either spirulina-fortified salad dressing containing 2 gr spirulina (SSD, n = 22) or a placebo salad dressing (PSD, n = 19) daily for eight weeks. This study was registered at https://www.irct.ir/ (the Iranian registry of clinical trials identifier: IRCT20200404046940N1).
Results: There was a change in body composition and anthropometric indices from baseline to 8 weeks. We observed that the mean change±SD of waist circumference after the SSD intervention (-2.86±4.02 cm) was significantly different from that of the PSD intervention (0.38±9.47 cm). Although no between-group difference was observed, a statistically significant reduction in body fat-free mass (FFM) occurred in the PSD group after the intervention. Meanwhile, within-group mean change±SD of body fat-free mass (FFM, 1.04±5.39 kg) and body fat mass (FM, -0.73±1.83 kg) was significant only in the SSD group. However, no significance between-group difference was observed in terms of FFM and FM changes.
Conclusion: The present study's findings suggest that consuming spirulina-fortified dressing can improve the status of risk factors associated with hypertension and cardiovascular diseases.