{"title":"慢性阻塞性肺疾病肺功能检查与颈动脉内膜-中膜厚度的关系。","authors":"Shahabaddin Sorouri, Maryam Naseri, Sepideh Hejazi","doi":"10.22088/cjim.16.3.487","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Studies have shown that carotid intima-media thickness (CIMT) is an indicator of cardiovascular events and mortality and its increase has correlation with severe airflow obstruction in patients with COPD. The aim of this study was to investigate the association between pulmonary function and CIMT in COPD patients.</p><p><strong>Methods: </strong>This study was performed on two groups of patients with and without COPD (cases & controls) who were referred to pulmonary clinics. Demographic, clinical, and laboratory tests were recorded in questionnaire. Spirometry was performed in cases and FVC, FEV1, and FEV1/FVC were measured. CIMT was determined via ultrasound.</p><p><strong>Results: </strong>Our results indicated that right carotid IMT was 0.51±0.112 mm and 0.65±0.131 mm in the control and case groups, respectively (p< 0.001). Left CIMT was 0.48±0.089 mm and 0.68±0.113 mm in the control and case groups, respectively (p< 0.001). FEV1 and FEV1/FVC had an inverse and significant correlation with IMT of the carotid (both right and left carotid).</p><p><strong>Conclusion: </strong>The results indicated an inverse association between carotid IMT and lung function test in COPD patients.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"16 3","pages":"487-492"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329360/pdf/","citationCount":"0","resultStr":"{\"title\":\"Pulmonary function test and carotid intima-media thickness in chronic obstructive pulmonary disease.\",\"authors\":\"Shahabaddin Sorouri, Maryam Naseri, Sepideh Hejazi\",\"doi\":\"10.22088/cjim.16.3.487\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Studies have shown that carotid intima-media thickness (CIMT) is an indicator of cardiovascular events and mortality and its increase has correlation with severe airflow obstruction in patients with COPD. The aim of this study was to investigate the association between pulmonary function and CIMT in COPD patients.</p><p><strong>Methods: </strong>This study was performed on two groups of patients with and without COPD (cases & controls) who were referred to pulmonary clinics. Demographic, clinical, and laboratory tests were recorded in questionnaire. Spirometry was performed in cases and FVC, FEV1, and FEV1/FVC were measured. CIMT was determined via ultrasound.</p><p><strong>Results: </strong>Our results indicated that right carotid IMT was 0.51±0.112 mm and 0.65±0.131 mm in the control and case groups, respectively (p< 0.001). Left CIMT was 0.48±0.089 mm and 0.68±0.113 mm in the control and case groups, respectively (p< 0.001). FEV1 and FEV1/FVC had an inverse and significant correlation with IMT of the carotid (both right and left carotid).</p><p><strong>Conclusion: </strong>The results indicated an inverse association between carotid IMT and lung function test in COPD patients.</p>\",\"PeriodicalId\":9646,\"journal\":{\"name\":\"Caspian Journal of Internal Medicine\",\"volume\":\"16 3\",\"pages\":\"487-492\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329360/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Caspian Journal of Internal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22088/cjim.16.3.487\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Caspian Journal of Internal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22088/cjim.16.3.487","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
背景：研究表明，颈动脉内膜-中膜厚度（CIMT）是COPD患者心血管事件和死亡率的一个指标，其升高与COPD患者严重气流阻塞有关。本研究的目的是探讨COPD患者肺功能与CIMT之间的关系。方法：本研究对两组转介到肺病诊所的COPD患者（病例和对照组）进行了研究。在问卷中记录人口学、临床和实验室检查结果。患者行肺活量测定，测量FVC、FEV1、FEV1/FVC。超声检测CIMT。结果：对照组和病例组右颈动脉IMT分别为0.51±0.112 mm和0.65±0.131 mm （p< 0.001）。对照组和病例组左CIMT分别为0.48±0.089 mm和0.68±0.113 mm （p< 0.001）。FEV1和FEV1/FVC与颈动脉（右颈和左颈）IMT呈显著负相关。结论：COPD患者颈动脉IMT与肺功能测试呈负相关。
Pulmonary function test and carotid intima-media thickness in chronic obstructive pulmonary disease.
Background: Studies have shown that carotid intima-media thickness (CIMT) is an indicator of cardiovascular events and mortality and its increase has correlation with severe airflow obstruction in patients with COPD. The aim of this study was to investigate the association between pulmonary function and CIMT in COPD patients.
Methods: This study was performed on two groups of patients with and without COPD (cases & controls) who were referred to pulmonary clinics. Demographic, clinical, and laboratory tests were recorded in questionnaire. Spirometry was performed in cases and FVC, FEV1, and FEV1/FVC were measured. CIMT was determined via ultrasound.
Results: Our results indicated that right carotid IMT was 0.51±0.112 mm and 0.65±0.131 mm in the control and case groups, respectively (p< 0.001). Left CIMT was 0.48±0.089 mm and 0.68±0.113 mm in the control and case groups, respectively (p< 0.001). FEV1 and FEV1/FVC had an inverse and significant correlation with IMT of the carotid (both right and left carotid).
Conclusion: The results indicated an inverse association between carotid IMT and lung function test in COPD patients.
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