99mtc -高锝切断鉴别Graves病与亚急性甲状腺炎。

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Caspian Journal of Internal Medicine Pub Date : 2025-06-23 eCollection Date: 2025-01-01 DOI:10.22088/cjim.16.3.513
Amir Gholami, Mahsa Sabbaghi, Hoda Shirafkan, Seyyed Hossein Mousavie Anijdan
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引用次数: 0

摘要

背景:甲状腺毒症的病因可以通过甲状腺对99mtc -高锝酸盐的摄取来确定。本研究的目的是计算甲状腺99mtc -高锝酸盐的临界值,以鉴别Graves病与亚急性甲状腺炎。方法:共纳入60例患者。根据甲状腺扫描结果,30例患者属于Graves组,其中30例被诊断为亚急性甲状腺炎。全面评估生化参数、甲状腺显像和甲状腺99mtc -高锝酸盐摄取百分比结果。结果:Graves组99mtc -高锝酸盐平均摄取百分比明显高于亚急性甲状腺炎组,差异有统计学意义(P)结论:99mtc -高锝酸盐摄取截断值1.1%可作为鉴别Graves病与亚急性甲状腺炎的一个有用指标,特别是在常规诊断方法难以区分两者的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

99mTc-pertechnetate cut-off to distinguish Graves' disease from subacute thyroiditis.

99mTc-pertechnetate cut-off to distinguish Graves' disease from subacute thyroiditis.

99mTc-pertechnetate cut-off to distinguish Graves' disease from subacute thyroiditis.

Background: The cause of thyrotoxicosis can be determined through the thyroid uptake of 99mTc-pertechnetate. The goal of the study was to calculate the cut-off value of 99mTc-pertechnetate of the thyroid gland for the differential diagnosis of Graves' disease from subacute thyroiditis.

Methods: A total of 60 patients were included in the study. Based on thyroid scan findings, 30 patients were in the Graves group and 30 of them had been diagnosed as subacute thyroiditis. Biochemical parameters, thyroid scintigraphy, and the percentage thyroidal 99mTc-pertechnetate uptake results were thoroughly assessed.

Results: The mean percentage 99mTc-pertechnetate uptake in Graves group was much higher than that of the subacute thyroiditis group, which was statistically significant (P <0.001). Receiver operating characteristic (ROC) analysis revealed that the uptake cut-off value of 1.1% had the sensitivity and specificity of 97% and 95%, respectively.

Conclusion: The findings depicted that the cutoff value of 1.1% for 99mTc-pertechnetate uptake could be a helpful index to differentiate Graves' disease from subacute thyroiditis, especially when it is difficult to distinguish between the two diseases using conventional diagnostic methods.

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来源期刊
Caspian Journal of Internal Medicine
Caspian Journal of Internal Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
1.90
自引率
7.10%
发文量
90
审稿时长
20 weeks
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